Klin Monbl Augenheilkd 2004; 221(5): 328-333
DOI: 10.1055/s-2004-812863
Originalarbeit

© Georg Thieme Verlag KG Stuttgart · New York

Comparing Phacoemulsification and Extracapsular Cataract Extraction in Eyes with Pseudoexfoliation Syndrome, Small Pupil, and Phacodonesis

Vergleich zwischen Phakoemulsifikation und extrakapsulärer Kataraktextraktion in Augen mit Pseudoexfoliationssyndrom, engen Pupillen und PhakodonesisJ. M. Katsimpris1 , I. K. Petropoulos2 , K. Apostolakis1 , D. Feretis1
  • 1Department of Ophthalmology, General Hospital of Patras “O Agios Andreas”, Patras, Greece (Director: Dr. D. Feretis)
  • 2Department of Ophthalmology, University Hospitals of Geneva, Geneva, Switzerland (Director: Prof. A. B. Safran)
Further Information

Publication History

received: 19.9.2003

accepted: 14.11.2003

Publication Date:
26 May 2004 (online)

Zusammenfassung

Hintergrund: Diese Studie hatte zum Ziel, die Häufigkeit der intra- und postoperativen Komplikationen zwischen der modernen Phakoemulsifikationstechnik und der extrakapsulären Kataraktextraktion bei Patienten mit Pseudoexfoliationssyndrom zu vergleichen. Patienten und Methoden: Diese prospektive randomisierte Studie schloss 94 Augen mit Katarakt, Pseudoexfoliationssyndrom, engen Pupillen und leichter bis mäßiger Phakodonesis ein. Diese Augen wurden in zwei Gruppen randomisiert. Alle Patienten der ersten Gruppe (47 Augen) wurden mittels standardisierter Phakoemulsifikationstechnik operiert: Irishaken, Anfärben der vorderen Kapsel, Kapsulorhexis und Implantation eines Kapselspannrings. Alle Patienten der zweiten Gruppe (47 Augen) wurden vom selben Chirurgen mittels einer klassischen extrakapsulären Kataraktoperation operiert. Hauptendpunkte dieser Studie waren die Häufigkeit eines intraoperativen Zonulafasernabrisses, einer Kapselruptur, eines Glaskörperverlusts und eines Korneaödems. Des Weiteren wurde der bestkorrigierte Visus bestimmt. Ergebnisse: Bei einem Auge (2,1 %) der ersten Gruppe und in 15 Augen (31,9 %) der zweiten Gruppe trat intraoperativ eine Dehiszenz der Zonulafasern auf (p < 0,001). Eine Ruptur der hinteren Kapsel mit oder ohne Dehiszenz der Zonulafasern trat in 2 Augen (4,2 %) der ersten Gruppe und in 8 Augen (17,0 %) der zweiten Gruppe (p < 0,05) auf. Auch ein Glaskörperverlust trat in der zweiten Gruppe häufiger auf als in der ersten Gruppe: 17 versus 4,2 %, p < 0,05. Der Unterschied des bestkorrigierten Visus fiel ebenfalls statistisch signifikant aus: In der ersten Gruppe war er besser (p < 0,001). Schlussfolgerungen: In den schwierigen Fällen einer Katarakt, vergesellschaftet mit Pseudoexfoliationssyndrom, engen Pupillen und Phakodonesis, bietet die moderne Operationstechnik mit kleiner Inzision im Vergleich zur extrakapsulären Kataraktextraktion bessere Resultate mit einer geringeren intra- und postoperativen Komplikationsrate.

Abstract

Background: This study aims to compare the frequency of intraoperative and postoperative complications between the modern phacoemulsification technique and the extracapsular cataract extraction technique in patients with pseudoexfoliation syndrome. Patients and methods: A prospective randomized study comprised 94 eyes with cataract, pseudoexfoliation syndrome, small pupil and slight to moderate phacodonesis. These eyes were randomly assigned into two groups. In the first group all patients (47 eyes) were operated on using a standard phacoemulsification technique (iris hooks, anterior capsule staining and capsular tension ring after capsulorhexis), while in the second group all patients (47 eyes) underwent a classic extracapsular cataract extraction. The main outcome measures were the frequency of intraoperative zonular tears, capsular rupture, vitreous loss and corneal edema, as well as the best-corrected visual acuity. Results: Intraoperative zonular separation was recorded in one eye (2.1 %) and in 15 eyes (31.9 %) for the first and second groups, respectively (P < 0.001). Posterior capsule rupture with or without zonular separation occurred in two eyes (4.2 %) of the first group and in eight eyes (17.0 %) of the second group (P < 0.05). Vitreous loss also had a higher rate in the second group (17.0 % versus 4.2 %, P < 0.05). The postoperative difference in best-corrected visual acuity was also significant between the two groups, being higher in patients operated on using phacoemulsification technique (P < 0.001). Conclusions: In the difficult cases of cataract associated with pseudoexfoliation syndrome, small pupil and phacodonesis, the modern small-incision cataract surgery provides better results with a low rate of intraoperative and postoperative complications when compared with the extracapsular cataract extraction technique.

References

  • 1 Asano N, Schlötzer-Schrehardt U M, Naumann G O. A histopathologic study of iris changes in pseudoexfoliation syndrome.  Ophthalmology. 1995;  102 1279-1290
  • 2 Bartholomew R S. Phakodonesis. A sign of incipient lens displacement.  Br J Ophthalmol. 1970;  54 663-666
  • 3 Bartholomew R S. Lens displacement associated with pseudocapsular exfoliation. A report on 19 cases in the Southern Bandu.  Br J Ophthalmol. 1970;  54 744-750
  • 4 Brazitikos P D, Roth A. Iris modifications following extracapsular cataract extraction with posterior chamber lens implantation.  J Cataract Refract Surg. 1991;  17 269-274
  • 5 Chee S P, Ti S E, Sivakumar M S. et al . Postoperative inflammation: Extracapsular cataract extraction versus phacoemulsification.  J Cataract Refract Surg. 1999;  25 1280-1285
  • 6 Chitkara D K, Smerdon D L. Risk factors, complications and results in extracapsular cataract extraction.  J Cataract Refract Surg. 1997;  23 570-574
  • 7 Cionni R J, Osher R H. Endocapsular ring approach to the subluxed cataractous lens.  J Cataract Refract Surg. 1995;  21 245-249
  • 8 Dark A J. Cataract extraction complicated by capsular glaucoma.  Br J Ophthalmol. 1979;  63 465-468
  • 9 Davison J A. Capsule contraction syndrome.  J Cataract Refract Surg. 1993;  19 582-589
  • 10 de Juan E Jr, Hickingbotham D. Flexible iris retractor.  Am J Ophthalmol. 1991;  111 776-777
  • 11 Dosso A A, Bonvin E R, Leuenberger P M. Exfoliation syndrome and phacoemulsification.  J Cataract Refract Surg. 1997;  23 122-125
  • 12 Drolsum L, Haaskjold E, Davanger M. Pseudoexfoliation syndrome and extracapsular cataract extraction.  Acta Ophthalmol. 1993;  71 765-770
  • 13 Fine I H, Hoffman R S. Phacoemulsification in the presence of exfoliation: challenges and options.  J Cataract Refract Surg. 1997;  23 160-165
  • 14 Freissler K, Küchle M, Naumann G O. Spontaneous dislocation of the lens in pseudoexfoliation syndrome.  Arch Ophthalmol. 1995;  113 1095-1096
  • 15 Freyler H, Radax U. Pseudoexfoliationssyndrom-ein Risikofaktor der modernen Kataraktchirurgie?.  Klin Monatsbl Augenheilkd. 1994;  205 275-279
  • 16 Gimbel H V, Sun R, Heston J P. Management of zonular dialysis in phacoemulsification and IOL implantation using the capsular tension ring.  Ophthalmic Surg Lasers. 1997;  28 273-281
  • 17 Guzek J P, Holm M, Cotter J B. Risk factors for intraoperative complications of 1000 extracapsular cataract cases.  Ophthalmology. 1987;  94 461-466
  • 18 Harris D J Jr. Exfoliation material on intraocular lens implants.  Arch Ophthalmol. 1996;  114 1429
  • 19 Helbig H, Schlötzer-Schrehardt U M, Noske W. et al . Anterior-chamber hypoxia and iris vasculopathy in pseudoexfoliation syndrome.  Ger J Ophthalmol. 1994;  3 148-153
  • 20 Forsius H. Exfoliation syndrome in various ethnic populations.  Acta Ophthalmologica Suppl. 1998;  184 71-85
  • 21 Jehan F S, Mamalis N, Crandall A S. Spontaneous late dislocation of intraocular lens within the capsular bag in pseudoexfoliation patients.  Ophthalmology. 2001;  108 1727-1731
  • 22 Konstas A G, Dimitrakoulias N, Kourtzidou O. et al . Frequency of exfoliation syndrome in Greek cataract patients.  Acta Ophthalmol Scand. 1996;  74 478-482
  • 23 Konstas A G, Tsatsos I, Kardasopoulos A. et al . Preoperative features of patients with exfoliation glaucoma and primary open-angle glaucoma. The AHEPA study.  Acta Ophthalmol (Copenh). 1998;  76 208-212
  • 24 Krupin T, Feitl M E, Bishop K I. Postoperative intraocular pressure rise in open angle glaucoma patients after cataract or combined cataract-filtration surgery.  Ophthalmology. 1989;  96 579-584
  • 25 Küchle M, Nguyen N, Hannappel E. The blood-aqueous barrier in eyes with pseudoexfoliation syndrome.  Ophthalmic Res. 1995;  27 (Suppl 1) 136-142
  • 26 Lamari F, Katsimpris J, Gartaganis S P. et al . Profiling of the aqueous humor in exfoliation syndrome by high-performance liquid chromatographic analysis of hyaluronan and galactosaminoglycans.  J Chromatogr B. 1998;  709 173-178
  • 27 Legler U F, Witschel B M. The capsular ring: a new device for complicated cataract surgery.  Ger J Ophthalmol. 1994;  3 265 (Abstract F12)
  • 28 Mackool R J. Small pupil enlargement during cataract extraction; a new method.  J Cataract Refracr Surg. 1992;  18 523-526
  • 29 Masket S. Avoiding complications associated with iris retractor use in small pupil cataract extraction.  J Cataract Refracr Surg. 1996;  22 168-171
  • 30 Menapace R, Findl O, Georgopoulos M. et al . The capsular tension ring:designs applications, and techniques.  J Cataract Refract Surg. 2000;  26 898-912
  • 31 Menkhaus S, Motschmann M, Kuchenbecker J. et al . Pseudoexfoliation syndrome and intraoperative complications in cataract surgery.  Klin Monatsbl Augenheilkd. 2000;  216 388-392
  • 32 Moreno J, Duch S, Lajara J. Pseudoexfoliation syndrome: clinical factors related to capsular rupture in cataract surgery.  Acta Ophthalmol. 1993;  71 181-184
  • 33 Naumann G O, Küchle M, Schonherr U. 543 - 545 . Pseudo-exfoliation syndrome as a risk factor for vitreous loss in extra-capsular cataract extraction. The Erlangen Eye Information Group.  Fortsch Ophthalmol. 1989;  86
  • 34 Naumann G O, Schlötzer-Schrehardt U M, Küchle M. Pseudoexfoliation syndrome for the comprehensive ophthalmologist.  Ophthalmology. 1998;  105 951-968
  • 35 Nishi O, Nishi K, Menapace R. Capsule bending ring for the prevention od capsular opacification: a preliminary report.  Ophthalmic Surg Lasers. 1998;  29 749-753
  • 36 Ritch R, Schlötzer-Schrehardt U M. Exfoliation syndrome.  Survey Ophthalmol. 2001;  45 265-315
  • 37 Scorolli L, Scorolli L, Campos E. et al . Pseudoexfoliation syndrome: a cohort study on intraoperative complications in cataract surgery.  Ophthalmologica. 1998;  212 278-280
  • 38 Skuta G L, Parrish R K, Hodapp E. et al . Zonular dialysis during extracapsular cataract extraction in pseudoexfoliation syndrome.  Arch Ophthalmol. 1987;  105 632-634
  • 39 Schlötzer-Schrehardt U M, Koka M R, Naumann G O. et al . Pseudoexfoliation syndrome. Ocular manifestation of a systemic disorder?.  Arch Ophthalmol. 1992;  110 1752-1756
  • 40 Tarkannen A. Pseudoexfoliation of the lens capsule: a clinical study of 418 patients with special reference to glaucoma, cataract, and changes of the vitreous.  Acta Ophthalmol Suppl. 1962;  71 9-98
  • 41 Wirbelauer C, Anders N, Pham D T. et al . Corneal endothelial cell changes in pseudoexfoliation syndrome after cataract surgery.  Arch Ophthalmol. 1998;  116 145-149

John M. Katsimpris, MD

215 Patron-Klaous str

26335 Patras

Greece

Phone: +30-2 61-03 35-5 63, +30-6 93-6 95-09 50

Fax: +30-2 61-03 27-0 34

Email: jkatsimpris@yahoo.com

Email: johnkatsjohnkats@netscape.net

    >