Severe Neutrophilia in an Infant with Persistent Pulmonary Hypertension of the Newborn

ABSTRACT

We report the case of a term male infant with severe persistent pulmonary hypertension of the newborn, who developed massive neutrophilia of unknown etiology. An extensive evaluation failed to disclose an obvious cause for his neutrophilia. A bone marrow aspirate was performed and was consistent with a leukemoid reaction. This paper reviews the neonatal leukemoid reaction and its significance.

KEYWORDS

Newborn - leukemoid reaction - persistent pulmonary hypertension - neutrophilia

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