Pharmacopsychiatry 2002; 35(2): 79-80
DOI: 10.1055/s-2002-25024
Case Report
© Georg Thieme Verlag Stuttgart · New York

Rivastigmin and Impaired Motor Function

M.  Heinze1 , D.  Andreae1 , R.  Grohmann2
  • 1Department of Psychiatry and Psychotherapy, Landesklinik Teupitz, Teupitz, Germany
  • 2Department of Psychiatry, Ludwig-Maximilian-Universität München, München, Germany
Further Information

Publication History

9. 5. 2001

17. 9. 2001

Publication Date:
12 April 2002 (online)

In this case study, we describe the case of an 88-year-old female patient diagnosed with Alzheimer's disease who developed a severe motor dysfunction as a side effect of rivastigmin treatment. There have been reports on motor dysfunctions caused by other choline esterase inhibitors.

References

  • 1 Amouyal-Barkate K, Bagheri-Charabiani H, Montastruc J L, Moulias S, Vellas B. Abnormal movements with donepezil in Alzheimer disease (letter).  Ann Pharmocother. 2000;  34 (11) 1347
  • 2 Anonymous . Cholinesterase inhibitor-induced Pisa syndrome.  International Drug Therapy Newsletter. 2000;  35 69
  • 3 Arai M. Parkinsonims onset in a patient concurrently using tiapride and donepezil.  Intern Med. 2000;  39 (10) 863
  • 4 Bourke D, Druckenbrod R W. Possible association between donepezil and worsening Parkinson's disease (letter).  Ann Pharmacother. 1998;  32 (5) 610-611
  • 5 Fontan A, Fanjul S, Bartolome M, Garcia-Ruiz P, Sanchez V, De Yebenes J G. Acetylcholinesterase inhibitors induce parkinsonism in patients with Alzheimer's disease.  Movement Disorders. 2000;  15 (3) 233
  • 6 Grohmann R, Ruether E, Engel R R, Hippius H. Assessment of Adverse Drug Reactions in Psychiatric Patients with the AMSP Drug Safety Program.  Pharmacopsychiat. 1999;  32 21 - 28
  • 7 Kwak Y T, Han I W, Baik J, Koo M S. Relation between cholinesterase inhibitor and Pisa syndrome.  Lancet. 2000;  355 2222
  • 8 Rösler M, Retz-Junginger P, Retz W. Alzheimer Demenz und Exelon. Thieme, Stuttgart New York 1998: 38-50

Dr. Martin Heinze

Landesklinik Teupitz

Buchholzer Straße 21

15755 Teupitz

Germany

Email: heinzem@zedat.fu-berlin.de

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