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Thromb Haemost 1979; 42(05): 1574-1579
DOI: 10.1055/s-0038-1657060
Original Article
Schattauer GmbH Stuttgart

Lectin Stimulation of Tissue Thromboplastin Activity in Human Monocytes in vitro

T Lyberg
The Department of Microbiology, Dental Faculty, University of Oslo, Blindem, Oslo, Norwayn
,
H Prydz
The Department of Microbiology, Dental Faculty, University of Oslo, Blindem, Oslo, Norwayn
› Author Affiliations
Further Information

Publication History

Received 04 December 1978

Accepted 12 October 1979

Publication Date:
18 February 2019 (online)

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Summary

Lectins (phytohaemagglutinin, concanavalin A and wheat germ agglutinin) trigger an increase in tissue thromboplastin activity of human monocytes in vitro. The presence of serum was not necessary and did not enhance the activity. The increase was inhibited by cycloheximide and actinomycin D, suggesting that de novo protein synthesis is involved.

 
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