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Thromb Haemost 1978; 39(03): 582-591
DOI: 10.1055/s-0038-1646731
Original Article
Schattauer GmbH Stuttgart

Tissue Thromboplastin Activity of Isolated Human Monocytes

H Prydz
Cell Pathology Division, Clinical Research Centre, Northwick Park, Harrow, Middlesex, England
,
A C Allison
Cell Pathology Division, Clinical Research Centre, Northwick Park, Harrow, Middlesex, England
› Author Affiliations
Further Information

Publication History

Received 05 October 1977

Accepted 03 December 1977

Publication Date:
12 July 2018 (online)

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Summary

Certain agents that induce spreading of or increased content or release of lysosomal enzymes from human monocytes also induce a dramatic increase in tissue thromboplastin content of the cells. The increase is inhibited by cycloheximide and actinomycin D and does not appear in granulocyte, lymphocyte or platelet populations treated in the same way. The effect of several other substances on the development of monocyte tissue thromboplastin activity is reported.

 

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