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Synthesis 2017; 49(23): 5251-5257
DOI: 10.1055/s-0036-1588486
DOI: 10.1055/s-0036-1588486
paper
Domino Reactions of 1-Aroyl-3,4-dihydroisoquinolines with α,β-Unsaturated Aldehydes
This work was supported by the Russian Foundation for Basic Research (grant 17-03-00605) and was financially supported by the Ministry of Education and Science of the Russian Federation (agreement no. 02.a03.21.0008).Further Information
Publication History
Received: 16 April 2017
Accepted after revision: 12 June 2017
Publication Date:
22 August 2017 (online)
Abstract
An efficient synthesis of pyrrolo[2,1-a]isoquinolines by a domino reaction from a variety of 3,4-dihydropyrrolo[2,1-a]isoquinolines and α,β-unsaturated aldehydes in the absence of catalyst in good yields under microwave irradiation, is reported.
Key words
domino reaction - dihydroisoquinolines - aldehydes - microwave irradiation - cytotoxic activitySupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1588486.
- Supporting Information
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