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Synfacts 2011(6): 0654-0654  
DOI: 10.1055/s-0030-1260360
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Tertiary and Quaternary Allyl- and Crotylsilanes

Contributor(s): Paul Knochel, Thomas Kunz
V. K. Aggarwal*, M. Binanzer, M. C. de Ceglie, M. Gallanti, B. W. Glasspoole, S. J. F. Kendrick, R. P. Sonawane, A. Vázquez-Romero, M. P. Webster
University of Bristol, UK
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Publication History

Publication Date:
19 May 2011 (online)

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Significance

The authors disclose synthetic methods for the preparation of tertiary and quaternary allyl- and crotylsilanes. A lithiation-borylation sequence of alkyl carbamates with silaboronates leads to tertiary silanes with high enantiomeric and diastereomeric ratios. The quaternary allyl­silanes were obtained after a sequential lithiation-silylation and lithiation-borylation procedure with comparable enantiomeric ratios.