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Synfacts 2010(10): 1205-1205  
DOI: 10.1055/s-0030-1258658
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

C-S Cross-Coupling with Iron/Graphite

Contributor(s): Yasuhiro Uozumi, Aya Tazawa
V. K. Akkilagunta, V. P. Reddy, K. R. Rao*
Indian Institute of Chemical Technology, Hyderabad, India
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Publication History

Publication Date:
22 September 2010 (online)

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Significance

An iron/graphite catalyst (Fe/Cg) was prepared by dispersion of Fe(acac)3 on graphite in THF (eq. 1). The catalyzed C-S cross-coupling of iodides 1 with thiols 2 gave the corresponding thioethers 3 in 59-98% yield (eq. 2, 26 examples).