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Synfacts 2010(10): 1130-1130  
DOI: 10.1055/s-0030-1258628
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

When Bipy Met Cucurbit[6]uril

Contributor(s): Timothy M. Swager, Carlos Cordovilla
M. K. Sinha, O. Reany, G. Parvari, A. Karmakar, E. Keinan*
Technion - Israel Institute of Technology, Haifa, Israel; The Scripps Research Institute, La Jolla, USA
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Publication History

Publication Date:
22 September 2010 (online)

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Significance

The authors describe the host-guest chemistry between 4-aminobipyridine derivatives and cucurbit[6]uril. The inclusion complexes show dramatic enhancements both in fluorescence intensity and quantum yields. Due to the ­reversibility of the complexation process, this ­effect can be used for the determination of binding constants and kinetic parameters in cascades of binding networks. This system can also be used for chemical sensing of transition metals and other ligands with relevance in biocatalysis.