Eur J Pediatr Surg
DOI: 10.1055/a-2743-4868
Review Article

Artificial Intelligence in Pediatric Surgery: From Diagnostics and Preoperative Planning to Risk Stratification: A Comprehensive Review of Current Applications

Autor*innen

  • Richard Gnatzy

    1   Department of Pediatric Surgery, Leipzig University, Leipzig, Germany
  • Xiaoyan Feng

    1   Department of Pediatric Surgery, Leipzig University, Leipzig, Germany
  • Daniel Graefe

    2   Department of Pediatric Radiology, Leipzig University, Leipzig, Germany
  • Oliver J. Deffaa

    1   Department of Pediatric Surgery, Leipzig University, Leipzig, Germany
  • Martin Lacher

    1   Department of Pediatric Surgery, Leipzig University, Leipzig, Germany

Abstract

Objective

Artificial intelligence (AI) is increasingly explored in pediatric surgical care, yet its translation into diagnostics and preoperative planning lags behind adult surgery. Unlike prior reviews, this study provides a comprehensive synthesis across four domains, diagnostics, preoperative planning, risk stratification, and surgical error prevention, highlighting recent advances and unmet challenges.

Methods

A narrative review of PubMed/MEDLINE (2020–2025) identified peer-reviewed studies on AI in pediatric surgery. Eligible articles addressed one of the four domains and were assessed for methodology, clinical applicability, and relevance to pediatric surgical patients.

Results

Diagnostic imaging is the most advanced field, with deep learning models for fracture detection and bone age assessment achieving accuracies up to 95% and near-expert agreement, though external validation is scarce. Preoperative planning benefits from AI-driven segmentation, 3D reconstruction, and virtual reality, with reports of altered surgical strategy in up to 8% of oncology cases, but evidence of outcome benefit is limited. Risk models for appendicitis and congenital heart surgery often surpass clinical scores, yet fewer than 10% have undergone external validation. Tools for error prevention, such as intelligent checklists and workflow monitoring, remain at the proof-of-concept stage. Across domains, most studies are retrospective, single-center, and methodologically heterogeneous.

Conclusion

AI demonstrates tangible potential to improve pediatric surgical diagnostics, planning, and safety. However, translation into clinical practice requires multicenter pediatric datasets, prospective validation, and transparent, interpretable models. By consolidating the most recent evidence across four domains, this review outlines both the opportunities and critical gaps that should be addressed for safe and effective adoption.



Publikationsverlauf

Eingereicht: 14. Oktober 2025

Angenommen: 08. November 2025

Artikel online veröffentlicht:
28. November 2025

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