DOI:
10.1055/s-00000084
Synthesis
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There is one report that involves copper-catalyzed intramolecular C–Br amination for the synthesis of several heterocycles including xanthines. However, only few examples were shown and it is unknown whether the approach is general and applicable for the xanthine synthesis: Szczepankiewicz BG. Rohde JJ. Kurukulasuriya R.
Org. Lett. 2005;
7: 1833
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