DOI: 10.1055/s-00000075

Seminars in Respiratory and Critical Care Medicine

Issue 01 · Volume 47 · February 2026 DOI: 10.1055/s-016-62982 Corticosteroids in Critically Ill Patients Guest Editors: Gianfranco Umberto Meduri, MD, FCCP, Antoni Torres, MD, PhD, FERS, FCCP, ATSF

Preface

  • 001
    Meduri, Gianfranco Umberto; Torres, Antoni:

    Monographic Issue on Glucocorticoid Therapy in Critical Illness and Respiratory Disease

    • Review Article

  • 003
    Meduri, Gianfranco Umberto:

    Glucocorticoids and GRα Signaling in Critical Illness: Phase-Specific Homeostatic Corrections Across Systems

    Supplementary Material (PDF)
  • 032
    Meduri, Gianfranco Umberto; Psarra, Anna-Maria G.:

    The Glucocorticoid System: A Multifaceted Regulator of Mitochondrial Function, Endothelial Homeostasis, and Intestinal Barrier Integrity

    Supplementary Material (PDF)
  • 047
    Meduri, Gianfranco Umberto:

    Factors Influencing Glucocorticoid Treatment Response: Mechanism-Based Strategies to Overcome Glucocorticoid Resistance and Restore GRα Function

  • 066
    Dequin, Pierre-François; Confalonieri, Marco:

    Glucocorticoid Treatment in Community-Acquired Pneumonia

    Open Access
  • 077
    Poulain, Cécile; Bouras, Marwan; Roquilly, Antoine:

    Glucocorticoid Treatment for Hospital-Acquired and Ventilator-Associated Pneumonia

  • 086
    Liu, Jiao; Xing, Qian; Pan, Xiaojun; Zhang, Sheng; Chen, Dechang; Annane, Djillali:

    Corticosteroid Treatment in Septic Shock

  • 098
    Guglielmi, Riccardo; Campanella, Antonio; Villar, Jesús; Torres, Antoni; Ferrando, Carlos:

    Corticosteroids for Acute Respiratory Distress Syndrome

  • 111
    Sartori, Filippo; Sartori, Giulia; Di Chiara, Claudia; Fantin, Alberto; Crisafulli, Ernesto:

    Glucocorticoid Treatment in Severe COPD Exacerbations: Biological Rationale, Clinical Effects, and Practical Advice

  • 122
    Pilia, María Florencia; Espejo-Castellanos, David; Romero-Mesones, Christian; Muñoz-Gall, Xavier; Ojanguren-Arranz, Iñigo:

    Glucocorticoid Treatment in Severe Asthma

  • 130
    Confalonieri, Paola; Reccardini, Nicolò; Kette, Stefano; Salton, Francesco:

    Complications Associated with Glucocorticoids Treatment in Critically Ill Patients

  • 140
    Meduri, Gianfranco Umberto; Lannini, Simone; Smit, Jim M.:

    Limitations in the Design of Critical Care Studies and Suggestions for Future Research Directions

    Supplementary Material (PDF)