DOI: 10.1055/s-00000083

Synlett

Ausgabe Radical Addition Reactions · Volume · 2026 DOI: 10.1055/s-015-62774

Radical Addition Reactions in Recent Years – Celebrating 50 Years of Giese Reaction

  • Sardar, Santosh Sing; De, Aramita; Pal, Satyajit; Sarkar, Subhankar; Santra, Sougata; Zyryanov, Grigory V.; Majee, Adinath:

    Visible-Light-Driven Denitrogenative C–C Bond Formation and Oxidative Difunctionalization of Vinyl Azides

    Image for article: Visible-Light-Driven Denitrogenative C–C Bond Formation and Oxidative Difunctionalization of Vinyl Azides
    Supporting Information (PDF)
  • Yamanomoto, Ken; Matsudaira, Tadachika; Akiyama, Takahiko:

    Metal- and Additive-Free Synthesis of α-Hydroxyamino Ketones Enabled by Organophotocatalyst

    Image for article: Metal- and Additive-Free Synthesis of α-Hydroxyamino Ketones Enabled by Organophotocatalyst
    Supporting Information (PDF)
  • Panigrahi, Ashutosh; Bathigowda, Pratik; Prahlad P; Pulukuri, Kiran Kumar:

    A Short and Scalable Total Synthesis of (±)-β-Eudesmol

    Image for article: A Short and Scalable Total Synthesis of (±)-β-Eudesmol
    Ergänzendes Material (PDF)
  • Evano, Gwilherm; Theunissen, Cédric:

    Copper-(Photo)Catalyzed Radical Reactions with Organic Halides

    Image for article: Copper-(Photo)Catalyzed Radical Reactions with Organic Halides
  • Hofer, Johannes; Pecho, Franziska; Bach, Thorsten:

    Photocatalytic Spirocyclization of 2-Alk-ω-enyl-Substituted Cycloalkane-1,3-diones

    Image for article: Photocatalytic Spirocyclization of 2-Alk-ω-enyl-Substituted Cycloalkane-1,3-diones
    Supporting Information (PDF)
  • Zhu, Zhengbo; Qian, Siran; Nicewicz, David A.:

    Divergent Functionalization of Alkynes Enabled by Organic Photoredox Catalysis

    Image for article: Divergent Functionalization of Alkynes Enabled by Organic Photoredox Catalysis
    Supporting Information (PDF) CIF File (OTHER)
  • Sanosa, Nil; Montiel-Cervantes, César; Rubio-Muñoz, Miguel; Sampedro, Diego; Funes-Ardoiz, Ignacio:

    Rationalizing the Regioselectivity of Azolation of Benzylic C–H Bonds under Photoredox Catalysis

    Image for article: Rationalizing the Regioselectivity of Azolation of Benzylic C–H Bonds under Photoredox Catalysis
    Supporting Information (PDF)
  • Kotha, Sambasivarao; Gupta, Naveen Kumar; Ansari, Saima; Singh, Deepshikha:

    Design of Molecular Diversity by Olefin Metathesis in Tandem with Other Reactions

    Image for article: Design of Molecular Diversity by Olefin Metathesis in Tandem with Other Reactions
  • Li, Zhi-Bo; Zhang, Jin; Shi, Yi-Ran; Li, Hong; Yang, Min-Ge; Zhu, Wen-Qing; Fan, Qiang-Wei; Li, Yang:

    AgSCF3 Radical Addition Based on an Oxidant-Free α,β-Amide (Trifluoromethyl)sulfanylation Reaction

    Image for article: AgSCF<sub>3</sub> Radical Addition Based on an Oxidant-Free α,β-Amide (Trifluoromethyl)sulfanylation Reaction
    Supporting Information (PDF)
  • Rourke, Michael J.; McGill, Matthew J.; Yang, Daniel; Farnam, Emelia J.; Zhu, Joshua L.; Scheidt, Karl A.:

    Photoredox-Catalyzed Radical–Radical Coupling of Potassium Trifluoroborates with Acyl Azoliums

    Image for article: Photoredox-Catalyzed Radical–Radical Coupling of Potassium Trifluoroborates with Acyl Azoliums
    Supporting Information (PDF)
  • Jacob, Clément; Annibaletto, Julien; Theunissen, Cédric:

    Photoredox-Catalyzed Reductive Activation of Ammonium Salts

    Image for article: Photoredox-Catalyzed Reductive Activation of Ammonium Salts
  • Ali, Kashif; Bera, Milan; Cho, Eun Jin:

    [3,3]-Rearrangements of N-Oxyindoles

    Image for article: [3,3]-Rearrangements of <i>N</i>-Oxyindoles
    Supporting Information (PDF)
  • Nowack, Marko H.; Moutet, Jules; Laursen, Bo W.; Gianetti, Thomas L.:

    Triangulenium Ions: Versatile Organic Photoredox Catalysts for Green-Light-Mediated Reactions

    Image for article: Triangulenium Ions: Versatile Organic Photoredox Catalysts for Green-Light-Mediated Reactions
    Supporting Information (PDF)
  • Das, Subhodeep; Banerjee, Amit; Das, Pritha; Jana, Ranjan:

    Visible-Light Organophotoredox-Catalyzed Phosphonoalkylation of Alkenes via Deaminative Three-Component Radical–Radical Coupling

    Image for article: Visible-Light Organophotoredox-Catalyzed Phosphonoalkylation of Alkenes via Deaminative Three-Component Radical–Radical Coupling
    Supporting Information (PDF)
  • Hung, Lang C.; McManus, Brennan D.; Taylor, Olivia R.; Bahamonde, Ana:

    Unraveling a Complex Mechanistic Picture of Photochemical Nickel-Catalyzed THF Arylation through Product Enantioselectivity Analysis

    Image for article: Unraveling a Complex Mechanistic Picture of Photochemical Nickel-Catalyzed THF Arylation through Product Enantioselectivity Analysis
  • Yadav, Pooja; Singh, Saumya; Shahid, M.; Gopinath, Purushothaman:

    Transition Metal/Photoredox-catalyzed Cascade Reactions Involving Annulation for Accessing Functionalized Heterocycles

    Image for article: Transition Metal/Photoredox-catalyzed Cascade Reactions Involving Annulation for Accessing Functionalized Heterocycles
  • Oger, Samuel; Evano, Gwilherm:

    Synthesis of Nitrogen Heterocycles by Intramolecular Radical Addition to Alkynes: A Systematic Study

    Image for article: Synthesis of Nitrogen Heterocycles by Intramolecular Radical Addition to Alkynes: A Systematic Study
    Ergänzendes Material (PDF)
  • Sátiro, Bárbara G.; Moura, Igor M. R.; Almeida, Cláudia L. A.; Freitas, Queila P. B.; Oliveira, Roberta A.; Menezes, Paulo H.:

    Silver Nitrate Catalyzed Sulfonylation of O-Propargyl Alkynes

    Image for article: Silver Nitrate Catalyzed Sulfonylation of <i>O</i>-Propargyl Alkynes
    Supporting Information (PDF) Primary Data (OTHER)
  • Fu, Yanhua; Zhang, Chao; Cai, Tao; Feng, Gaofeng:

    Generation of Carbamoyl Radicals and 3,4-Dihydroquinolin-2(1H)-ones Enabled by Iron Photoredox Catalysis

    Image for article: Generation of Carbamoyl Radicals and 3,4-Dihydroquinolin-2(1<i>H</i>)-ones Enabled by Iron Photoredox Catalysis
    Supporting Information (PDF)
  • Gan, Yu; Li, Xuejiao; Zhou, Jun-Feng; Ye, Baihua:

    Selective Open-Shell Nickel Catalysis Driven by Redox-Transmetalation

    Image for article: Selective Open-Shell Nickel Catalysis Driven by Redox-Transmetalation
  • Shigehisa, Hiroki:

    Cyclization via Metal-Catalyzed Hydrogen Atom Transfer/Radical-Polar Crossover

    Image for article: Cyclization via Metal-Catalyzed Hydrogen Atom Transfer/Radical-Polar Crossover
  • Wheatley, Emilie; Silvi, Mattia:

    One Carbon at a Time: Unlocking Iterative Carboxylic Acid Homologation

    Image for article: One Carbon at a Time: Unlocking Iterative Carboxylic Acid Homologation
  • Zhang, Xue; Liang, Nuoyu; Li, Ruining; Sun, Zhankui:

    Application of Halogen-Bonding Catalysis for Markovnikov-Type Hydrothiolation of Alkenes

    Image for article: Application of Halogen-Bonding Catalysis for Markovnikov-Type Hydrothiolation of Alkenes
    Supporting Information (PDF)
  • Bhatt, Kamal; Seidel, Daniel:

    Cyclic Imine-BF3 Complexes as Precursors for Functionalized Azacycles

    Image for article: Cyclic Imine-BF<sub>3</sub> Complexes as Precursors for Functionalized Azacycles
  • Yang, Xingheng; Zhang, Chi; Wang, Cheng-Qiang; Feng, Chao:

    Expedient Access to Structural Complexity via Radical β-Fragmentation of N–O Bonds

    Image for article: Expedient Access to Structural Complexity via Radical β-Fragmentation of N–O Bonds
  • Lou, Yizhe; Tregear, Maud; Longmire, David; Chu, John C. K.:

    Overcoming Substrate Bias in Radical Addition: Selective C3-Functionalisation of Indoles

    Image for article: Overcoming Substrate Bias in Radical Addition: Selective C3-Functionalisation of Indoles
    Supporting Information (PDF)
  • Yang, Huan; Ye, Shi-Qi; Shao, Gang; Chen, Jun-Shen; Wang, Guan-Wu:

    Mechanosynthesis of Fullerotetrahydroquinolines by Copper-Mediated sp3 C–H Functionalization of N,N-Dimethylanilines with [60]Fullerene

    Image for article: Mechanosynthesis of Fullerotetrahydroquinolines by Copper-Mediated sp<sup>3</sup> C–H Functionalization of <i>N</i>,<i>N</i>-Dimethylanilines with [60]Fullerene
    Supporting Information (PDF)
  • Brals, Jeremy; D’Arcy-Evans, Nicholas; McGuire, Thomas M.; Watson, Allan J. B.:

    Organophotocatalytic Radical–Polar Cross-Coupling of Styrylboronic Acids and Redox-Active Esters

    Image for article: Organophotocatalytic Radical–Polar Cross-Coupling of Styrylboronic Acids and Redox-Active Esters
    Open Access
    Supporting Information (PDF)
  • Kato, Yamato; Kanoh, Miho; Shioiri, Takayuki; Matsugi, Masato:

    Metal-Free Selective Air-Oxidation of Sulfides to Sulfoxides Using 2,2′-Azobis-(2,4-dimethyl-4-methoxyvaleronitrile) (V-70) and Isobutyraldehyde

    Image for article: Metal-Free Selective Air-Oxidation of Sulfides to Sulfoxides Using 2,2′-Azobis-(2,4-dimethyl-4-methoxyvaleronitrile) (V-70) and Isobutyraldehyde
    Supporting Information (PDF)
  • Shang, Xiao-Jie; Chu, Run; Luo, Rui; Zhang, Yanjiang; Liu, Zhong-Quan:

    A Free-Radical Decarboxylative Coupling of Cinnamic Acids with Acetonitrile

    Image for article: A Free-Radical Decarboxylative Coupling of Cinnamic Acids with Acetonitrile
    Supporting Information (PDF)
  • Sakamoto, Kaori; Oda, Wakana; Kobayashi, Yusuke; Matsuo, Jun-ichi; Furuta, Takumi; Hamada, Shohei:

    Accelerating Effect of the Addition of HFIP on the Oxidation of Alcohols Using TEMPO/PIDA

    Image for article: Accelerating Effect of the Addition of HFIP on the Oxidation of Alcohols Using TEMPO/PIDA
    Supporting Information (PDF)