DOI: 10.1055/s-00000083

Synlett

Issue Small-Molecule MedChem · Volume · 2025 DOI: 10.1055/s-015-61587

Emerging Trends in Organic Chemistry: A Focus on India

Small Molecules in Medicinal Chemistry

Thaker, Aanal; Patel, Shrusti; Dey, Rajdeep; Shaw, Suman; Bhatt, Hardik; Patel, Bhumika; Chaube, Udit: Advancements in mTOR Inhibitors for Non-Small-Cell Lung Cancer: Mechanisms, Efficacy, and Future Perspectives
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Candito, David A.; Simov, Vladimir; Liu, Ping; Ardolino, Michael J.; Martinot, Theodore; Lyons, Thomas; Qi, Ji; Yin, Jingjun; Hao, Jinglai; Hu, Bin; Chen, Meng; Zhang, Jun; Lam, Yu-hong; Fuller, Peter H.; Ellis, J. Michael; Maddess, Matthew: A Concise Synthesis of a Key Azabicyclo[2.1.1]hexane Building Block for N-Heteroaryl Indazole LRRK2 Kinase Inhibitors
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Kumar, Ch. N. S. Sai Pavan; Jayathirtha, Vaidya Rao: Bioactive Molecules via Morita–Baylis–Hillman Chemistry
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Seaton, Wesley B.; West, Clayton; Burke, Susan J.; Schilletter, William A.; Tade, Opeyemi O.; Collier, J. Jason; Campagna, Shawn R.: Design, Synthesis, and Biological Evaluation of Thioether Steroids as Glucocorticoid Receptor Modulators
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Ito, Toshiya; Kinoshita, Kazutomo; Tomizawa, Masaki; Shinohara, Shojiro; Nishii, Hiroki; Tanaka, Hiroshi; Kuramoto, Shino; Oikawa, Nobuhiro: Development of a Novel Tropomyosin Receptor Kinase Inhibitor Based on Structure–Activity Relationships: Identification of a Promising Clinical Candidate
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Chaudhury, Subhabrata; Wetzel, Edward A.; Elmansy, Mohamed F.; Hanson, Alicia M.; Brown-Ford, Sandra; Gleason, Alexandra; Perera, K. L. Iresha Sampathi; Sem, Daniel S.; Donaldson, William A.: Analogues of the Potent and Selective ERβ Agonist trans-4-(4-Hydroxyphenyl)cyclohexanemethanol: Synthesis and Evaluation
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Alaeddini, AmirHossein; Karimian, Somaye; Noori, Milad; Dastyafteh, Navid; Mohammadi-Khanaposhtani, Maryam; Ghomi, Minoo Khalili; Bararjanian, Morteza; Iraji, Aida; Javanshir, Shahrzad; Larijani, Bagher; Ranjbar, Parviz Rashidi; Mahdavi, Mohammad: Design, Synthesis, Enzymatic Inhibition, and Antioxidant Activity of New 4-Phenylpiperazin-phenoxy-1,2,3-triazol-acetamide Derivatives as Tyrosinase Inhibitors
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Goel, Kapil Kumar; Singhal, Peeush; Marianesan, Arockia Babu; Pandey, Sarvesh Kumar; Kumar, Roshan; Singh, Thakur Gurjeet; Tyagi, Yogita; Gaidhane, Shilpa; Singh, Mahendra Pratap; Dwivedi, Ashish Ranjan: A Decade of Piperazine-Based Small Molecules Approved by U.S. FDA: Exploring the Medicinal Chemistry Impact of this Versatile Pharmacophore
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Garg, Aakriti; Bhattacharya, Bireswar; Samanta, Uttam; Singha, Subhankar; Ghosh, Dipanjan; Bhowmik, Subhendu; Jaisankar, Parasuraman; Gupta, Sreya: Phototriggered Migration of Indole-Based Cationic Fluorophore from Mitochondria to Nucleolus in Live Cells
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Chandra, Devesh; Sachin, Sachin; Rav, Shourabh; Sharma, Upendra: Quinoline-Based FDA-Approved Drugs: Synthetic Route and Clinical Uses
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Beveridge, Julia; Söderström, Marcus; Balestri, Lorenzo Jacopo Ilic; Prieto-Díaz, Rubén; Gutierrez-de-Teran, Hugo; Odell, Luke R; Hallberg, Mathias; Larhed, Mats; Gising, Johan: Benzylhydroxamic Acids as IRAP Inhibitors: Sulfonamide Variations
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Khanka, Sonu; Rawat, Kundan S.; Pandey, Priyanka; Pal, Shyamal; Vats, Ravi P.; Rathur, Rajat; Sharma, Kriti; Dipali, Divya; Singh, Divya; Goel, Atul: An Efficient Synthesis of 3-Aryl-2H-chromene Derivatives as Potential Bone Anabolic Agents
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Sakamoto, Masaharu; Kai, Seriha; Tateishi, Hiroshi; Biswas, Tanima; Sakamoto, Takashi; Teshima, Misaki; Iwanaga, Misaki; Nishikawa, Akiko; Sakamoto, Arisa; Shimozono, Rie; Kameyama, Hiroki; Nambu, Masami; Masunaga, Takuya; Anraku, Kensaku; Fujita, Mikako; Otsuka, Masami: Oxaprozin and SB-431542 Hybrid Molecule Inhibits Fibrosis and Cancer Cell Migration
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Toledano-Pinedo, Mireia; Diez-Iriepa, Daniel; Porro-Pérez, Alicia; Schäker-Hübner, Linda; Hanl, Maria; Samadi, Abdelouahid; Almendros, Pedro; Iriepa, Isabel; Rodríguez-Fernández, M. Mercedes; Griñán-Ferré, Christian; Siwek, Agata; Wolak, Małgorzata; Satała, Grzegorz; Bojarski, Andrzej J.; Doroż-Płonka, Agata; Handzlik, Jadwiga; Godyń, Justyna; Knez, Damijan; Gobec, Stanislav; Więckowska, Anna; Hansen, Finn K.; Marco-Contelles, José: Contilistat, a New Multitarget Small Polyfunctionalized Indole Derivative
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Thien, Nguyen Duc; Ngoc, Hoang Kim; Nam, Nguyen-Hai; Anh, Duong Tien; Baecker, Daniel: A Novel Strategy for the Synthesis of N-Alkylated Oxindoles
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Ghosh, Priyam; Mukhopadhyay, Sayantani; Singh, Mrinalini; Ghosh, Siddhartha Sankar; Iyer, Parameswar Krishnan: Exploring the Dual Therapeutic Potential of a Photoactivatable AIEgen in Cancer and Alzheimer’s Disease
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