Synfacts

Issue 02 · February 2023

Recommend Journal

Issue
Synform
A18
SYNFORM ISSUE 2023/02 FREE ACCESS

Full Text

PDF (4255 kb)
Synthesis of Natural Products
z0111
All PDFs of this category

Full Text

PDF (332 kb)
0111
Syntheses of Preussomerins

Full Text

HTML

PDF (75 kb)
0112
Total Synthesis of (−)-Sinulochmodin C

Full Text

HTML

PDF (89 kb)
0113
Total Synthesis of (–)-Peyssonnoside A FREE ACCESS

Full Text

HTML

PDF (126 kb)
0114
Synthesis of (+)-Periglaucine C

Full Text

HTML

PDF (85 kb)
0115
Total Synthesis of (+)-Havellockate

Full Text

HTML

PDF (95 kb)
0116
Total Synthesis of the Grayanoid (–)-Principinol C

Full Text

HTML

PDF (80 kb)
0117
Total Synthesis of (+)-Monensin FREE ACCESS

Full Text

HTML

PDF (127 kb)
Synthesis of Heterocycles
z0119
All PDFs of this category

Full Text

PDF (380 kb)
0119
Multigram Synthesis of ^pivZPhos Ligand

Full Text

HTML

PDF (98 kb)
0120
Asymmetric Reductive Transamination for the Synthesis of Chiral Piperidines

Full Text

HTML

PDF (68 kb)
0121
Room Temperature Metal-Free Heteroaryl Hydrogenation FREE ACCESS

Full Text

HTML

PDF (149 kb)
0122
Ru(II)-Catalyzed Synthesis of Bridged Tetracycles via C–H Allylation and [3+2] Dipolar Cycloaddition

Full Text

HTML

PDF (89 kb)
0123
Synthesis and Application in Ni-Mediated C–C Cross-Couplings of a Modular Series of Novel Ligands

Full Text

HTML

PDF (72 kb)
0124
Scalable Synthesis of Enantiopure Bicyclic Fluorinated Pyrrolidinol

Full Text

HTML

PDF (91 kb)
0125
Enantioselective Transannular Reaction of Macrocyclic Sulfonamides

Full Text

HTML

PDF (80 kb)
0126
Two-Step Regioselective Trifluoropropylation of Azoles

Full Text

HTML

PDF (79 kb)
0127
Pyrimidines to Pyrazoles Under Mild Conditions

Full Text

HTML

PDF (76 kb)
0128
Merging Known Pharmacophores: Synthesis of Substituted N-Indolizines

Full Text

HTML

PDF (81 kb)
0129
Building 3-Borylated Pyrrolidines via 1,3-Dipolar Cycloaddition

Full Text

HTML

PDF (79 kb)
0130
Efficient Ni-Mediated Cyanation of (Hetero)Aryl Halides under Homogeneous Conditions

Full Text

HTML

PDF (72 kb)
0131
Three-Step, One-Pot Regioselective C-3 Trifluoromethylation of Quinolines

Full Text

HTML

PDF (74 kb)
0132
Elemental Sulfur-Mediated Annulation of Enaminones to Access 2-Aminofurans and 2-Aminthiophenes

Full Text

HTML

PDF (79 kb)
Synthesis of Materials and Unnatural Products
z0133
All PDFs of this category

Full Text

PDF (401 kb)
0133
A Giant Photonic Ring FREE ACCESS

Full Text

HTML

PDF (153 kb)
0134
Halogen-Atom Transfer Enabled Indole Synthesis

Full Text

HTML

PDF (79 kb)
0135
[4]Acenes from Double Cyclizations of Fluoroalkene

Full Text

HTML

PDF (67 kb)
0136
Tetraaryl Dihydropentalenes

Full Text

HTML

PDF (83 kb)
0137
Pyridinium-Promoted Hydroarylation of Aryl Alkynes

Full Text

HTML

PDF (82 kb)
0138
A Squarephaneic Tetraanhydride for Porous Materials

Full Text

HTML

PDF (70 kb)
0139
Corralarenes: Conjugated Tubular Macrocycles

Full Text

HTML

PDF (79 kb)
0140
Lossen Rearrangement to Thiocarbamates

Full Text

HTML

PDF (65 kb)
0141
A Single-Step Atroposelective Construction

Full Text

HTML

PDF (86 kb)
0142
B/N-Doped Acenaphthylene and Acenaphthene

Full Text

HTML

PDF (68 kb)
0143
Azaborole Helicenes with Double Helical Axes

Full Text

HTML

PDF (87 kb)
0144
Easy Access to Azatriphenylenes

Full Text

HTML

PDF (98 kb)
Metals in Synthesis
z0145
All PDFs of this category

Full Text

PDF (739 kb)
0145
Atroposelective Ring-Closing Metathesis of Stereo-dynamic Trienes to Access Chiral Binaphthalenes FREE ACCESS

Full Text

HTML

PDF (129 kb)
0146
Enantioselective Benzylic C–H Cyanation by Merging Electrophoto- and Copper Catalysis

Full Text

HTML

PDF (73 kb)
0147
Synthesis of Diastereo- and Enantioenriched Homoallylic Alcohols with a Chiral CF₃- and F-Bound Carbon FREE ACCESS

Full Text

HTML

PDF (134 kb)
0148
Syntheses of Diarylmethanes via Silver or Synergic Silver/Scandium-Catalyzed Benzannulation Reactions

Full Text

HTML

PDF (97 kb)
0149
Dual Photoredox/Copper Catalysis Enables Asymmetric Cyanation via 1,4-Heteroaryl Migration

Full Text

HTML

PDF (79 kb)
0150
Carbon and Silyl Electrophiles Hand in Hand: Nickel-Catalyzed Regioselective Carbosilylation of Acrylonitrile

Full Text

HTML

PDF (68 kb)
0151
Enantioconvergent Carboxylation of Racemic Benzylic (Pseudo)Halides under Nickel Catalysis

Full Text

HTML

PDF (85 kb)
0152
Enantioselective Pd(0)-Catalyzed Carbonitration Reaction via Alkyl–Pd(II)–ONO₂Reductive Elimination

Full Text

HTML

PDF (81 kb)
0153
Amination of Aryl Halides Enabled by Dual Nickel/Red-Light-Metallaphotoredox Catalysis

Full Text

HTML

PDF (75 kb)
0154
Three-Component Cross-Electrophile Silylarylation of 1,3-Dienes under Nickel Catalysis

Full Text

HTML

PDF (82 kb)
0155
Hydroalkenylation of Strained 3- and 4-Membered Carbocycles under Photoinduced Palladium Catalysis

Full Text

HTML

PDF (74 kb)
0156
Pd-Catalyzed Synthesis of Tetrasubstituted Phthalans from Haloarenes, Alkynes, and Protic Nucleophiles

Full Text

HTML

PDF (76 kb)
0157
Palladium Domino Cyclization/β-Carbon Elimination Reaction Generating Axially Chiral Compounds

Full Text

HTML

PDF (83 kb)
0158
Cross-Coupling of Alkyl Fluorides with Lipshutz Cuprates under Aluminum Iodide-Mediated C–F Bond Activation

Full Text

HTML

PDF (69 kb)
0159
Ruthenium-Catalyzed Isomerization of 3°-Allylic Alcohols via a β-Aryl Elimination

Full Text

HTML

PDF (87 kb)
0160
Enantioselective 1,6-Addition of Chiral Boryl–Alkyl Nucleophiles to para-Quinone Methides

Full Text

HTML

PDF (87 kb)
0161
Synthesis of 1,1-Diarylalkanes via a Photoinduced Cobalt-Catalyzed Hydroarylation of Styrenes

Full Text

HTML

PDF (76 kb)
0162
Rhodium-Catalyzed Asymmetric Hydrosilylation of β,β-Disubstituted Enamides to α-Aminosilanes

Full Text

HTML

PDF (107 kb)
0163
Hydrodecarboxylation of Carboxylic Acids under Cooperative Iron–Thiol Catalysis

Full Text

HTML

PDF (71 kb)
0164
Copper-Catalyzed Synthesis of N-Cyanomethyl Amide via a Claisen Rearrangement

Full Text

HTML

PDF (91 kb)
0165
Synthesis of Borylated Allenes via Iron-Catalyzed Functionalization of Propargylic Acetates

Full Text

HTML

PDF (75 kb)
0166
Access to α-Chiral Tertiary Amines by Cobalt-Catalyzed Enantioselective Hydroamination of Arylalkenes

Full Text

HTML

PDF (84 kb)
0167
Stereoselective Rhodium-Catalyzed Enyne–Cyclobutanone Annulation

Full Text

HTML

PDF (93 kb)
0168
Ru(II)-Catalyzed Three-Component Reaction Toward the Synthesis of Chromeno[4,3-c]pyrazol-4-ones

Full Text

HTML

PDF (89 kb)
0169
Kinetic Resolution/Enantioselective Alkynylation of Alkyl Allylic Alcohols under Iridium Catalysis

Full Text

HTML

PDF (79 kb)
0170
Enantioselective Photocatalyzed Radical Addition to Ketones

Full Text

HTML

PDF (79 kb)
Polymer-Supported Synthesis
z0171
All PDFs of this category

Full Text

PDF (326 kb)
0171
Metal-Free Oxidative C–C Bond Cleavage of Ketones Promoted by Biomass-Derived Carbons FREE ACCESS

Full Text

HTML

PDF (116 kb)
0172
α-Alkylation of Acetamides with Alcohols Catalyzed by Ruthenium Nanoparticles

Full Text

HTML

PDF (90 kb)
0173
Photocatalytic C−S Coupling Using Colloidal Carbon Dots and NiBr₂∙dtbbpy

Full Text

HTML

PDF (72 kb)
0174
Decarbonylation of 1,2-Diketones Catalyzed by Au–Pd Nanoparticles Supported on CeO₂

Full Text

HTML

PDF (73 kb)
0175
Phosphorylation of Tetrahydroisoquinolines and Oxidation of Sulfides by 4CzIPN-Based Porous Polymers

Full Text

HTML

PDF (83 kb)
0176
Chemoselective Hydrogenation of Nitroarenes by Cobalt Single-Atom Catalysts

Full Text

HTML

PDF (81 kb)
0177
Suzuki Coupling and Heck Reaction Using Pd NPs Supported on Catechol−Functionalized MWCNTs

Full Text

HTML

PDF (123 kb)
0178
Ring-Opening Hydrosilylation or Dehydrogenative Silylation of Cyclopropyl Aldehydes and Ketones

Full Text

HTML

PDF (80 kb)
0179
A³-Coupling Catalyzed by Gold Nanoparticles Supported on γ-AlO(OH)

Full Text

HTML

PDF (86 kb)
0180
Hydrogenation of Aromatic Rings and Cleavage of Etheric C–O Bonds by a Ruthenium Single-Atomic Catalyst

Full Text

HTML

PDF (66 kb)
0181
Photocatalytic Oxidation of Benzylamines and Thioanisoles by a Buta-1,3-diene-Linked COF

Full Text

HTML

PDF (84 kb)
Organo- and Biocatalysis
z0183
All PDFs of this category

Full Text

PDF (309 kb)
0183
N-Heterocyclic Carbene (NHC) Catalysis Permits Diastereoselective Radical Aminoacylation of Olefins

Full Text

HTML

PDF (83 kb)
0184
Chiral Phosphoric Acid-Catalyzed Diels–Alder Reaction of 2-Trifluoroacetamido-1,3-Dienes and Enones

Full Text

HTML

PDF (87 kb)
0185
Hypervalent Iodine Catalyst Grants Access to 1,4-Difunctionalized Fluorinated Olefins FREE ACCESS

Full Text

HTML

PDF (125 kb)
0186
Conformational Fixation of Organocatalyst in Metal-Organic Framework Permits Improved Enantiocontrol

Full Text

HTML

PDF (182 kb)
Innovative Drug Discovery and Development
z0187
All PDFs of this category

Full Text

PDF (859 kb)
0187
“Click-to-Release” Biorthogonal Chemophototherapy FREE ACCESS

Full Text

HTML

PDF (494 kb)
0188
Ervogastat: A Potent and Selective Inhibitor of DGAT2 for the Treatment of NASH

Full Text

HTML

PDF (71 kb)
0189
Multivariate Linear Regression Informs Ligand Design to Improve the Synthesis of a KRAS Inhibitor FREE ACCESS

Full Text

HTML

PDF (138 kb)
0190
A Comprehensive Study of Myxobacterial Corramycin

Full Text

HTML

PDF (79 kb)
0191
Total Synthesis of Pentosinane

Full Text

HTML

PDF (69 kb)
0192
Fluorinated Peptoid-Capped Histone Deacetylase Inhibitors

Full Text

HTML

PDF (78 kb)
0193
Metabolically Stable HDAC Inhibitors with Improved Selectivity Utilizing a Novel Zinc-Binding Group

Full Text

HTML

PDF (66 kb)
0194
Glycoconjugation of Andrographolide Improves Neuroprotective Potential

Full Text

HTML

PDF (112 kb)
0195
Design and Synthesis of a Potent, Orally Active Direct Renin Inhibitor for Hypertension

Full Text

HTML

PDF (74 kb)
0196
High-Affinity Brain-Penetrant Ph-HTBA for CaMKIIα Modulation

Full Text

HTML

PDF (90 kb)
0197
Taming Heterogeneous Reactions to Access PROTAC Linkers Using Flow Chemistry

Full Text

HTML

PDF (79 kb)
0198
Highly Efficient Construction of Polyols Through Boronic Ester Homologation – Synthesis of Bahamaolide A

Full Text

HTML

PDF (135 kb)
0199
A Green High-Yielding 7-Step Synthesis of Nirmatrelvir

Full Text

HTML

PDF (82 kb)
Peptide Chemistry
z0201
All PDFs of this category

Full Text

PDF (323 kb)
0201
Late-Stage Functionalization for the Construction of Proline Skeleton in Peptides FREE ACCESS

Full Text

HTML

PDF (119 kb)
0202
N-Indole-Protected Peptide Synthesis

Full Text

HTML

PDF (79 kb)
0203
Pd-Catalyzed Deuteration of Amino Acids

Full Text

HTML

PDF (78 kb)
0204
Cu-Catalyzed Hydrogermylation of Dehydro Amino Acids

Full Text

HTML

PDF (98 kb)
0205
Three-Component Coupling to Afford α,α-Diaryl Amino Acids

Full Text

HTML

PDF (85 kb)
0206
α-Amino Acid Amidation Using a Silicon Reagent

Full Text

HTML

PDF (77 kb)
0207
Indolylation of N-2-Nitrophenylsulfenyl Imino Peptides

Full Text

HTML

PDF (76 kb)
0208
C–H Functionalization at the β-Position of Dehydroamino Acids

Full Text

HTML

PDF (79 kb)
0209
Chemoselective Cleavage of the tert-Butoxycarbonyl Group from Di-tert-butylimidodicarbonate FREE ACCESS

Full Text

HTML

PDF (123 kb)
Flow Chemistry
z0211
All PDFs of this category

Full Text

PDF (81 kb)
0211
Synthesis of Fentanyl Using Photoredox Catalysis under Flow

Full Text

HTML

PDF (81 kb)
Most Read
Archive
Articles by Category
Free Sample Issue

Journal

More About This Journal
Synfacts Videos
Editorial Board
Editorial Office
Brochure

Authors

Instructions for Authors

Subscription

Subscription Information & Contacts
Institutional Licensing

Nobel Prize 2016

Instructions for Authors

Journals
Book Series
Login
Help
Portal
Return to Classic Website

German English

Thieme E-Books & E-Journals is a service of Georg Thieme Verlag and Thieme Medical Publishers, Inc.
© Georg Thieme Verlag KG

Imprint | Privacy policy statement

Your Current IP Address: 216.73.216.149