Metabolically Stable HDAC Inhibitors with Improved Selectivity Utilizing a Novel Zinc-Binding Group

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Synfacts 2023; 19(02): 0193
DOI: 10.1055/s-0042-1753237

Innovative Drug Discovery and Development

Contributor(s):

Antonia F. Stepan (Roche)

,

Nadine Kuhl (MSD)

,

Ulrich Lücking (FoRx Therapeutics)

hydroxamic acids - trifluoromethylketones - trifluoropyruvamides - bioisosteres - zinc-binding groups

Article published online:
17 January 2023

Georg Thieme Verlag KG
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