DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 09 · Volume 106 · 2011 DOI: 10.1055/s-008-36051

Invited Editorial Focus

389
Streiff, Michael B.: Prothrombin complex concentrates for reversal of vitamin K antagonists: Assessing the risks

New Technologies, Diagnostic Tools and Drugs

391
Jilma-Stohlawetz, Petra; Gilbert, James C.; Gorczyca, Monika E.; Knöbl, Paul; Jilma, Bernd: A dose ranging phase I/II trial of the von Willebrand factor inhibiting aptamer ARC1779 in patients with congenital thrombotic thrombo - cytopenic purpura
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
521
Riddell, Anne; Abdul-Kadir, Rezan; Pollard, Debra; Tuddenham, Edward; Gomez, Keith: Monitoring low dose recombinant factor VIIa therapy in patients with severe factor XI deficiency undergoing surgery
528
Keogh, Claire; Wallace, Emma; Dillon, Ciara; Dimitrov, Borislav D.; Fahey, Tom: Validation of the CHADS2 clinical prediction rule to predict ischaemic stroke
Online Supplementary Material (PDF) Online Supplementary Material (PDF)

Review Article

391
Christensen, Thomas Decker; Larsen, Torben Bjerregaard; Hjortdal, Vibeke E.: Self-testing and self-management of oral anticoagulation therapy in children
398
Gater, Adam; Thomson, Thomas A.; Strandberg-Larsen, Martin: Haemophilia B: impact on patients and economic burden of disease

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

405
Mahan, Charles E.; Holdsworth, Mark T.; Welch, Shawn M.; Borrego, Matt; Spyropoulos, Alex C.: Deep-vein thrombosis: A United States cost model for a preventable and costly adverse event
416
Alessi, Marie-Christine; Nicaud, Viviane; Scroyen, Ilse; Lange, Celine; Saut, Noemie; Fumeron, Frederic; Marre, Michel; Lantieri, Olivier; Fontaine-Bisson, Benedicte; Juhan-Vague, Iréne; Balkau, Beverley; Tregouet, David-Alexandre; Morange, Pierre-Emmanuel; D.E.S.I.R. Study Group: Association of vitronectin and plasminogen activator inhibitor-1 levels with the risk of metabolic syndrome and type 2 diabetes mellitus
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
423
Venetz, Carmen; Jiménez, David; Méan, Marie; Aujesky, Drahomir: A comparison of the original and simplified Pulmonary Embolism Severity Index
429
Dentali, Francesco; Marchesi, Chiara; Pierfranceschi, Matteo Giorgi; Crowther, Mark; Garcia, David; Hylek, Elaine; Witt, Daniel M.; Clark, Nathan P.; Squizzato, Alessandro; Imberti, Davide; Ageno, Walter: Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists
439
Dentali, Francesco; Ageno, Walter; Rancan, Elena; Donati, Alberto V.; Galli, Luca; Squizzato, Alessandro; Venco, Achille; Mannucci, Pier Mannuccio; Manfredini, Roberto: Seasonal and monthly variability in the incidence of venous thromboembolism
448
Pieters, Marlien; Maat, Moniek P. M. De; Jerling, Johann C.; Hoekstra, Tiny; Kruger, Annamarie: Fibrinogen concentration and its role in CVD risk in black South Africans – effect of urbanisation

Platelets and Blood Cells

457
Moertl, Deddo; Berger, Rudolf; Hammer, Alexandra; Hutuleac, Raisa; Koppensteiner, Renate; Kopp, Christoph W.; Steiner, Sabine: Dose-dependent decrease of platelet activation and tissue factor by omega-3 polyunsaturated fatty acids in patients with advanced chronic heart failure
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
466
Zufferey, Anne; Reny, Jean-Luc; Combescure, Christophe; Moerloose, Philippe de; Sanchez, Jean-Charles; Fontana, Pierre: Platelet reactivity is a stable and global phenomenon in aspirin-treated cardiovascular patients
475
Bartsch, Ingrid; Sandrock, Kirstin; Lanza, Francois; Nurden, Paquita; Hainmann, Ina; Pavlova, Anna; Greinacher, Andreas; Tacke, Uta; Barth, Michael; Busse, Anja; Oldenburg, Johannes; Bommer, Martin; Strahm, Brigitte; Superti-Furga, Andrea; Zieger, Barbara: Deletion of human GP1BB and SEPT5 is associated with Bernard-Soulier syndrome, platelet secretion defect, polymicrogyria, and developmental delay
484
Pan, Ruimin; Wang, Jianhui; Nardi, Michael A.; Li, Zongdong: The inhibition effect of anti-GPIIIa49–66 antibody on megakaryocyte differentiation
491
Spectre, Galia; Arnetz, Lisa; Östenson, Claes-Göran; Brismar, Kerstin; Li, Nailin; Hjemdahl, Paul: Twice daily dosing of aspirin improves platelet inhibition in whole blood in patients with type 2 diabetes mellitus and micro- or macrovascular complications

Endothelium and Vascular Development

500
Madonna, Rosalinda; Salerni, Sara; Schiavone, Deborah; Glatz, Jan F.; Geng, Yong-Jian; Caterin, Raffaele De: Omega-3 fatty acids attenuate constitutive and insulin-induced CD36 expression through a suppression of PPARα/γ activity in microvascular endothelial cells
Online Supplementary Material (PDF) Online Supplementary Material (PDF)

Cardiovascular Biology and Cell Signalling

511
Silvain, Johanne; Pena, Ana; Vignalou, Jean-Baptiste; Hulot, Jean-Sébastien; Galier, Sophie; Cayla, Guillaume; Bellemain-Appaix, Anne; Barthélémy, Olivier; Beygui, Farzin; Bal-dit-Sollier, Claire; Drouet, Ludovic; Weisel, John W.; Montalescot, Gilles; Collet, Jean-Phillippe: FXIII-A Leu34 genetic variant in premature coronary artery disease: A genotype – phenotype case control study

Letters to the Editor

548
Krawiec, Piotr; Gluszko, Piotr; Kwasny-Krochin, Beata; Undas, Anetta: Decreased protein Z levels in patients with rheumatoid arthritis: Links with inflammation
554
Höckner, Jana: Megakaryocyte-restricted expression of the Cre recombinase
554
Parrilla, Roberto: Rebuttal to the letter by J. Höckner: ‘Megakaryocyte gene targeting mediated by restricted expression of recombinase Cre’
561
Rosenkranz, Anke C.; Schrör, Karsten; Rauch, Bernhard H.: Direct inhibitors of thrombin and factor Xa attenuate clot-induced mitogenesis and inflammatory gene expression in human vascular smooth muscle cells
563
Visser, Marieke C. H. de; Roshani, Sara; Rutten, Julie W.; Vlieg, Astrid van Hylckama; Vos, Hans L.; Rosendaal, Frits R.; Reitsma, Pieter H.: Haplotypes of VKORC1, NQO1 and GGCX, their effect on activity levels of vitamin K-dependent coagulation factors, and the risk of venous thrombosis

Letters to the editor

551
Brennan, Stephen O.; Roncolato, Fernando: Novel fibrinogen (Bβ401Gly→Val) presents as dys- or hypodysfibrinogenaemia due to alterations in sialic acid content
555
Orban, Martin; Byrne, Robert A.; Hausleiter, Jörg; Laugwitz, Karl-Ludwig; Sibbing, Dirk: Massive thrombus burden with recurrence of intracoronary thrombosis early after stenting and delayed onset of prasugrel action in a patient with ST-elevation myocardial infarction and cardiac shock
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
558
Pietrys, Danuta; Balwierz, Walentyna; Iwaniec, Teresa; Vorjohann, Silja; Neerman-Arbez, Marguerite; Undas, Anetta: Two different fibrinogen gene mutations associated with bleeding in the same family (AαGly13Glu and γGly16Ser) and their impact on fibrin clot properties: Fibrinogen Krakow II and Krakow III