Synfacts
Issue 05 · May 2017
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Synform
A72
SYNFORM
ISSUE 2017/05
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Synthesis of Natural Products and Potential Drugs
z0449
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0449
Concise Total Synthesis of (±)-Verrubenzospirolactone
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0450
Synthesis of Madangamine Alkaloids
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0451
Synthesis of LY2623091
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0452
Synthesis of EFdA via Enzymatic Desymmetrization
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0453
Synthesis of an Androgen Receptor Antagonist
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0454
Asymmetric Synthesis of (−)-Communesin F
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0455
Synthesis of
ent
-Kaurane Diterpenoids
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0456
Synthesis of (+)-γ-Actinorhodin
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0457
Synthesis of a GPR40 Modulator
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0458
Synthesis of ABT-341
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0459
Synthesis of BMS-960
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0460
Total Synthesis of (+)-Dalesconol A and B
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0461
Total Syntheses of
Kopsia
Indole Alkaloids
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0462
Asymmetric Synthesis of an AZD7594 Intermediate Using Flow Catalysis
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Synthesis of Heterocycles
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0463
Functionalized Propellanes, Azetidines, Cyclobutanes, and Chiral Cyclopentanes
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0464
Synthesis of 2,5-Disubstituted Oxazoles
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0465
De Novo Synthesis of Polyaryl Salicyl Esters
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0466
Indole Synthesis by an Intramolecular aza-Stetter Reaction
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0467
Synthesis of 2,3-Disubstituted Pyridines by Transition-Metal-Free Amination
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0468
Cobalt-Mediated Synthesis of Quinolin-2(1
H
)-ones
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0469
Palladium-Catalyzed Synthesis of 4-(2-Haloaryl)-1,2,3-triazoles
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0470
Homonucleosides by Amination/Cyclization of Sulfanyl 1,6-Diynes
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0471
1,2,4-Triazines by the Reaction of
N
-Tosylhydrazones with Aziridines
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0472
Intramolecular 2-Aminoimidazole Synthesis from Guanidine
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0473
Synthesis of Lactams from Imines and Homophthalic Anhydride
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0474
Electroorganic Synthesis of Pyrimido-[4,5-
b
]indole Derivatives
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0475
Copper-Catalyzed Route to Indazolo-[3,2-
b
]quinazolinones
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0476
Photoredox-Promoted Anti-Markovnikov Hydroamination of Nonactivated Olefins
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0477
Fused Heterocycles by an Amine-Catalyzed aza-Diels–Alder Reaction
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0478
Carbonylative Benzannulation Route to Substituted Benzofurans
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Synthesis of Materials and Unnatural Products
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0479
Friedel–Crafts Benzylation of Deactivated Benzylic Alcohols
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0480
Stable Ynamines into Push-Pull Thiophenes
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0481
Ironing out a Better Route to PAHs
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0482
Intramolecular Oxidative Dehydrogenative Coupling
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0483
Flower Power: Daisy Chains as Molecular Muscles
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0484
Do Not Disturb the π Network
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0485
Mild and Convenient? Make it in situ!
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0486
A Simpler Approach for Atom- and Pot-Economical Synthesis of PAHs
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0487
Unsymmetrically Substituted Dibenzo-pentalenes
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0488
Why ‘Knot’?
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0489
Cross-Coupled Corannulenes
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0490
O-Fused PAHs: Colorful Molecules Made in Europe
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Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
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0491
Asymmetric Palladium-Catalyzed α-Arylation of α-Fluorooxindoles
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0492
Iridium-Catalyzed Intramolecular Asymmetric Dearomatization
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0493
Palladium-Catalyzed Asymmetric C–H Functionalizations of Isobutanamides
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0494
Ruthenium-Catalyzed Asymmetric Hydrogenation of Isocoumarins
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0495
Palladium-Catalyzed Reductive Heck Reaction
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0496
Copper-Catalyzed Stereoselective Hydro-alkylation of Alkynes with α-Bromo Esters
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0497
Zinc-Catalyzed Asymmetric Synthesis of Trisubstituted Aziridines
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0498
Rhodium-Catalyzed Diastereoselective Synthesis of α,β-Diamino Acid Derivatives
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0499
Ruthenium-Catalyzed Asymmetric Synthesis of Polysubstituted Pyrrolidines
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0500
Iridium-Catalyzed Enantioselective Hydroarylation of Vinyl Ethers
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0501
Dynamic Kinetic 1,2-Addition of Boronic Acids to Racemic α-Keto Esters
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0502
Fluoroalkylated Isoxazolidines by 1,3-Dipolar Cycloaddition
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0503
Scandium-Catalyzed Bromoamination of Alkenes
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0504
Copper-Catalyzed Enantioselective Radical Amino- and Azidocyanation
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0505
Carbohelicenes by Gold-Catalyzed Asymmetric Cyclization
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0506
Enantioselective B–H Insertion Using Alkynes as Carbene Precursor
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0507
Ruthenium-Catalyzed Cyclopropanation of Diazo Weinreb Amides
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0508
Rhodium-Catalyzed Asymmetric Addition of 1,3-Diketones to Allenes
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0509
Enantioselective Vinylogous and Bisvinylogous Mannich-Type Reaction
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0510
Chiral Amine/Palladium Dual Catalysis: Terminal Addition to Allenes
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0511
Palladium-Catalyzed Asymmetric Cinnamylation
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0512
Copper-Catalyzed Alkyne Conjugate Addition by the Use of Tunable P,N-Ligands
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0513
Rhodium-Catalyzed Asymmetric Hydroamination of Alkenes
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0514
Ruthenium-Catalyzed Asymmetric Hydrogenation of Phenanthridines
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0515
Palladium(II)-Catalyzed C–H Amination with a Chiral Phosphoric Acid
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0516
Asymmetric Rhodium(III)-Catalyzed Decarboxylative Michael Addition
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0517
Iridium-Catalyzed Asymmetric Ring Opening with Carboxylic Acid Nucleophiles
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0518
Rhodium(III)-Catalyzed C–H Annulation of Indoles with Diazo Compounds
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0519
Rhodium-Catalyzed Enantioselective Hydroaminomethylation of Olefins
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Metal-Mediated Synthesis
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0521
Cross-Coupling of
N
-Mesyl-Acitivated Amides
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0522
Ruthenium(II)-Catalyzed C–H Arylation of Tertiary Amides with Organosilanes
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0523
Preparation of Functionalized Imidazoles via Oxalyl Boronates
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0524
Synthesis of α-Branched
N
-Acylamines
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0525
Synthesis of Heteroarene Sulfonic Esters
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0526
Suzuki–Miyaura Coupling of Sterically Hindered Aryl Carbonates
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0527
Metal-Free C–H Alkylation of Heteroarenes with Alkyltrifluoroborates
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0528
Enantioselective Allylic Substitution with 2-Methylpyridines
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0529
Catalytic Friedel–Crafts C–H Borylation of Electron-Rich Arenes
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0530
3-Amidation of Indoles
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0531
Transition-Metal-Free C3-Arylation
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0532
Stereoselective Arylation of Amino Aldehydes
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0533
Hydrosilylation of Terminal Alkynes
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0534
Acyl Tellurides and their Radical–Radical Homocoupling Reactions
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0535
Palladium-Catalyzed Formylation
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Organo- and Biocatalysis
z0537
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0537
Intramolecular [4+2] Cycloaddition of
ortho-
Quinone Methides Generated In Situ
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0538
Bioelectrochemical Nitrogen Reduction
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0539
Biocatalytic Synthesis of β-Hydroxydioxinones
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0540
N-Heterocyclic Carbene Catalyzed Synthesis of 3,4-Dihydrocoumarins
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0541
Asymmetric Alkylation of Anthrones for the Total Synthesis of Viridicatumtoxin B
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0542
Reusable Polymer-Based Catalysts for the Asymmetric Steglich Rearrangement
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0543
Biocatalytic Enantioselective Hydroalkoxylation
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0544
Catalytic γ-Addition of 2-Allylazaarenes to Isatins and Trifluoromethyl Ketones
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Polymer-Supported Synthesis
z0545
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0545
Chiral Piperazines by Phosphoric Acid/Metal Nanoparticle Catalysis
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0546
Synthesis of Benzo[4,5]imidazo[1,2-
a
]pyrim-idines Catalyzed by Double-Layer Hydroxide
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0547
Synthesis of
N
-Alkoxyacylimidoyl Halides by Using NaHSO
4
/SiO
2
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0548
H-Y Zeolite Promoted Condensation of Furans with Anilines
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0549
Hydration of Alkynes by Using a Sulfonated Aromatic Resin
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0550
Palladium-Catalyzed Phenoxycarbonylation of Aryl Iodides
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0551
Palladium/Boron Nitride Catalyzed Carbon–Carbon Coupling Reactions
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0552
Gold-Catalyzed Transfer Hydrogenation of N-Heterocycles with Formic Acid
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0553
Palladium-Catalyzed Continuous-Flow Tsuji–Trost Coupling
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0554
Palladium-Containing Carbocatalyst for Suzuki–Miyaura Coupling in Water
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0555
Ruthenium-Photocatalyzed Transfer Hydrogenation of Aldehydes and Ketones
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0556
Cobalt-Catalyzed Oxidation of Alcohols to Aldehydes, Esters, and Nitriles
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0557
Nickel–Molybdenum Oxide Catalyzed Chemoselective Reduction of Nitroarenes
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0558
Synthesis of Hantzsch 1,4-Dihydropyridines Catalyzed by Sulfated Polyborate
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0559
A Neodymium/Sodium-Based Catalyst for Asymmetric Flow Nitroaldol Reaction
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0560
Zirconium-Catalyzed Cycloaddition of Carbon Dioxide and Epoxides
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Erratum
561
Iron-Catalyzed Enantioselective Synthesis of BINOLs
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