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DOI : 10.1055/s-00000094

Zeitschrift für Gastroenterologie

Issue 01 · Volume 53 · January 2015 DOI: 10.1055/s-005-28378

31. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber
München, 30.–31. Januar 2015

Kongresspräsidentin: Prof. Dr. Ulrike Protzer – Kongresssekretär: Prof. Dr. Jacob Nattermann

Abstracts (HTML) List of Authors

3. Metabolism/Transport

A3_1

Sarina, P; Kristy, A; Hall, RA; Lammert, F; Green, RM: Identification of eQTLs for hepatic Xbp1 s and Socs3 gene expression in mice fed a high-fat, high caloric diet

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A3_2

Ramadori, P; Drescher, H; Schumacher, F; Erschfeld, S; Fragoulis, A; Wruck, C; Trautwein, C; Kroy, D; Streetz, K: Lack of hepatic keap-1 ameliorates steatosis through a negative LXR modulation without altering the innate immune response in a diet-induced model of nonalcoholic steato-hepatitis

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A3_3

Qvartskhava, N; Lang, P; Pozdeev, V; Görg, B; Häussinger, D: Leberspezifischer Glutaminsynthetase-Knockout induziert Hyperammonämie und oxidativen Stress im Maushirn

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A3_4

Karababa, A; Görg, B; Häussinger, D: Expression von Seneszenzbiomarker in mit Ammoniak behandelten kultivierten Astrozyten und in post mortem Hirngewebe von Leberzirrhosepatienten mit hepatischer Enzephalopathie

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A3_5

Matz-Soja, M; Schmidt-Heck, W; Guthke, R; Gebhardt, R: A new modelling approach for Gli transcription factor network in hepatocytes

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A3_6

Gautheron, J; Vucur, M; Reisinger, F; Canbay, A; Tacke, F; Trautwein, C; Heikenwälder, M; Luedde, T: A novel function of necroptosis in Non-Alcoholic Steatohepatitis

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A3_7

Böttger, J; Schmidt-Heck, W; Matz-Soja, M; Thiel, C; Hofmann, U; Vlaic, S; Guthke, R; Gebhardt, R: A quantitative metabolomic profiling and corresponding modeling approach of hepatocytes with activated Wnt/ß-Catenin signaling

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A3_8

Gehrke, N; Mann, A; Alt, Y; Schad, A; Waisman, A; Hövelmeyer, N; Galle, PR; Wörns, MA; Schattenberg, JM: Bcl-3 reguliert die hepatische Lipo- und Gluconeogenese in einem murinen, hochkalorischen Fütterungsmodell der nicht-alkoholischen Fettlebererkrankung (NAFLD)

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A3_9

Rennert, C; Aleithe, S; Böttger, J; Matz-Soja, M; Gebhardt, R: Cooperation of Hedgehog and Wnt/β-Catenin signalling in regulation of steroidogenesis in the liver

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A3_10

Caliskan, S; Wewering, F; Gerding, B; Luch, A; Zellmer, S: Cytotoxicity of anisidine in hepatic cell lines

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A3_11

Hermanns, HM; Mais, C; Walter, S; Geier, A: Endocytosis of the signal transducing receptor gp130 as mechanism to fine-tune IL-6 responses

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A3_12

Schraplau, A; Schewe, B; Neuschäfer-Rube, F; Ringel, S; Neuber, C; Kleuser, B; Püschel, GP: Enhanced Phenobarbital-induced Thyroid Hormone Breakdown in Hepatocytes by Benzo[a]pyren-dependent Induction of the Constitutive Androstane Receptor

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A3_13

Mahli, A; Saugspier, M; Thasler, WE; Müller, M; Hellerbrand, C: ERK and p38 activation are central mediators of irinotecan-induced steatohepatitis

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A3_14

Spomer, L; Gertzen, CGW; Häussinger, D; Gohlke, H; Keitel, V: Experimental validation of the predicted TGR5 binding mode model

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A3_15

Jördens, M; Görg, B; Keitel, V; Häussinger, D: Expression des Multidrug Resistance Protein 4 in mit Ammoniak behandelten kultivierten Rattenastrozyten und in post mortem Hirnproben von Leberzirrhosepatienten mit HE

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A3_16

Rupp, C; Rupp, AK; Sauer, P; Bode, KA; Leopold, Y; Kloeters-Plachky, P; Weiss, KH; Altevogt, P; Stremmel, W; Gotthardt, DN: Identification and proteomic profiling of biliary exosomes

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A3_17

Mahli, A; Thasler, WE; Müller, M; Seitz, HK; Cederbaum, AI; Hellerbrand, C: Identification of cytochrome CYP2E1 as critical mediator of alcohol effects on steatotic hepatocytes

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A3_18

Missing, L; Häussinger, D; Bode, JG: Inhibition of the transcriptional regulation of CDCA-induced BSEP expression by IL-1β involves the IL-1β triggered activation of autocrine chemokine circuits

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A3_19

Uerlings, R; Boaru, SG; Weiskirchen, S; Zimmermann, A; Matusch, A; Merle, U; Stremmel, W; Weiskirchen, R: Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) in trace metal imaging of experimental and clinical metal disorders

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A3_20

Stremmel, WR; Staffer, S; Wannhoff, A; Pathil-Warth, A; Chamulitrat, W: Lysophosphatidylcholine (LPC) as central player for hepatic fat accumulation and inflammation: implication for the pathogenesis of NASH

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A3_21

Arnold, K; Thiel, C; Marbach, E; Böttger, J; Matz-Soja, M; Sales, S; Shevchenko, A; Gebhardt, R: Neue Aspekte der Regulation des Lipidmetabolismus während der Entstehung von NAFDL

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A3_22

Straub, BK; Dries, V; Kasper, HU; Schömig, E; Drebber, U; Langner, C; Dienes, HP; Schirmacher, P: Phenprocoumon-induced liver injury

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A3_23

Dayoub, R; Lupke, M; Hofmann, U; Melter, M; Weiss, TS: Reduced HNF3b (FOXA2) levels in steatosis leads to diminished expression of anti-lipoapoptotic protein ALR

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A3_24

Schönefeld, K; Matz-Soja, M; Böttger, J; Seibel, P; Gebhardt, R: Regulation of energy metabolism in hepatocytes with induced steatosis

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A3_25

Teufel, A; Itzel, T; Erhart, W; Brosch, M; Kim, YO; Schönfels, W von; Herrmann, A; Brückner, S; Stickel, F; Chavakis, T; Hellerbrand, C; Becker, T; Schreiber, S; Schuppan, D; Schafmeier, C; Hampe, J: Representation of human non-alcoholic fatty liver disease in murine models

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A3_26

Jahn, D; Sutor, D; Hermanns, HM; Schmitt, J; Geier, A: Retinoic acid amplifies the FXR-dependent FGF19 gene expression in human enterocyte-like HT-29 cells by a bi-phasic mechanism

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A3_27

Krawczyk, M; Wunsch, E; Lütjohann, D; Lammert, F; Milkiewicz, P: Serum sterol levels indicate distorted cholesterol homeostasis in cirrhotic patients with primary biliary cirrhosis

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A3_28

Lee, SML; Demmel, M; Hauner, M; Schiergens, T; Werner, J; Thasler, WE: The effect of extended transportation time on the quality of freshly isolated human liver cells

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A3_29

Jahn, D; Gildein, L; Fleet, JC; Schmitt, J; Hermanns, HM; Geier, A: Vitamin D3 acts on the gut-liver-adipose tissue axis to modulate obesity and associated metabolic and inflammatory changes in diet-induced obese mice

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A3_30

Neuschäfer-Rube, F; Lieske, S; Birkenfeld, AL; Püschel, GP: Xenobiotic-dependent induction of the tricarboxylate carrier Slc13a5 in primary cultures of rat hepatocytes

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A3_31

Oenarto, J; Görg, B; Castoldi, M; Häussinger, D: Zerebrale miRNA-Expressionsänderungen bei hepatischer Enzephalopathie

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