DOI: 10.1055/s-00000175

Arzneimittelforschung

Ausgabe 02 · Volume 53 · Februar 2003 DOI: 10.1055/s-002-22658

CNS-active Drugs · Hypnotics · Psychotropics · Sedatives

73
Jindal, Dharam Paul; Piplani, Poonam; Fajrak, Hassan; Prior, Chris; Marshall, Ian G.: Synthesis and Biological Evaluation of 16β-Pyrrolidinosteroidal Derivatives
80
Washio, Takuo; Kohsaka, Kazuhiro; Arisawa, Hirohiko; Masunaga, Hiroaki; Nagatsuka, Shin-ichiro; Satoh, Yoshiaki: Pharmacokinetics and Metabolism of Radiolabelled SNI-2011, a Novel Muscarinic Receptor Agonist, in Healthy Volunteers
87
Kees, Frieder; Jehkul, Andreas; Bucher, Michael; Mair, Georg; Kiermaier, Josef; Grobecker, Horst: Bioavailability of Opipramol from a Film-coated Tablet, a Sugar-coated Tablet and an Aqueous Solution in Healthy Volunteers

Antiallergic Drugs · Antiasthmatics · Antitussives · Bronchodilators · Bronchosecretogogues · Mucolytics

93
Llupià, Josep; Gras, Jordi; Llenas, Jesús: Comparative Antiallergic Effects of Second-generation H1-Antihistamines Ebastine, Cetirizine and Loratadine in Preclinical Models

Antiemetics · Gastrointestinal Drugs · Urologic Drugs · Uricosuric Drugs

98
Yoshikawa, Takashi; Mine, Yukiko; Morikage, Kazuo; Yoshida, Naoyuki: Pharmacological Profile of AS-9705, a Novel Benzotriazolecarboxamide Derivative, as a Gastroprokinetic Agent with Potent Anti-emetic Activity

Antibiotics · Antiviral Drugs · Chemotherapeutics · Cytostatics

107
Baraldi, Pier Giovanni; Tabrizi, Mojgan Aghazadeh; Pavani, Maria Giovanna; Nuñez, Maria del Carmen; Makaeva, Rimma; Gambari, Roberto; Colla, Paolo La; Romagnoli, Romeo: Design, Synthesis and in vitro Cytotoxicity of a cis-Dichloroplatinum (II) Complex Linked to the Minor Groove Binder Stallimycin
114
Gökhan, Nesrin; Erdoğan, Hakkı; Durlu, N. Tugˇba; Demirdamar, Rümeysa; Özalp, Meral: Synthesis and Evaluation of Analgesic, Anti-inflammatory and Antimicrobial Activities of 6-Acyl-3-piperazinomethyl-2-benzoxazolinones
121
Guzmán, Antonio; García, Concepción; Marŕna, Ana-Paz; Willoughby, Chris; Demestre, Isabel: Developmental Toxicity Studies of the Quinolone Antibacterial Agent Irloxacin in Rats and Rabbits
126
Müller, Rainer; Böttger, Christina; Wichmann, Georg: Suitability of Cefotiam and Cefuroxime Axetil for the Perioperative Short-term Prophylaxis in Tonsillectomy Patients

Special Themes

133
Kandemirli, Fatma; Tokay, Nesrin; Shvets, Nataly M.; Dimoglo, Anatoly S.: Electronic-Topological Study of the Structure-Activity Relationships in a Series of Steroids with Mineralocorticoid Binding Affinity

Information on Patents

139
Habernickel, Valentin J.: The Pharma Market as Reflected by Patents

Book Reviews

143
Book Reviews