Pflanzliche Sterole als Nahrungsmitteladditiva zur Prävention kardiovaskulärer Erkrankungen

Zusammenfassung

Sterol-angereichtere Nahrungsmittel „Functional Foods” werden zur Senkung des Cholesterinspiegels von vielen Menschen konsumiert. Ein Wirksamkeitsbeleg von Phytosterolen im Hinblick auf kardiovaskuläre Ereignisse liegt nicht vor. Das Krankheitsbild der Sitosterolämie, epidemiologische Daten und neue experimentelle Ergebnisse ergeben Hinweise, dass pflanzliche Sterole negative kardiovaskuläre Effekte induzieren könnten. Vor einer generellen Empfehlung dieser Produkte sind daher weitere Daten zur Wirksamkeit und Sicherheit erforderlich.

Summary

„Functional foods” supplemented with plant sterols are advertised and added to regular meals to reduce serum cholesterol concentrations. The effects of increased phytosterol levels on cardiovascular diseases, however, are not known. Findings in patients with sitosterolemia, data from epidemiological studies, and experimental data from animal studies suggest that plant sterols may potentially exert negative cardiovascular effects. Additional studies investigating relevant clinical endpoints are needed before a diet supplemented with plant sterols can be recommended in the prevention of cardiovascular diseases.

Schlüsselwörter

pflanzliche Sterole - Prävention - Ernährung - kardiovaskuläres Risiko - Nahrungsergänzungsstoffe

Key words

plant sterols - prevention - nutrition - cardiovascular risk - functional food

Literatur

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