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Synthesis 2008(9): 1455-1459  
DOI: 10.1055/s-2008-1072534
PAPER
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Norpandamarilactonines, Pandamarilactonines, and ­Pandanamine

Sanjib Gogoi, Narshinha P. Argade*
Division of Organic Chemistry, National Chemical Laboratory, Pune 411008, India
e-Mail: np.argade@ncl.res.in;
Further Information

Publication History

Received 9 January 2008
Publication Date:
27 March 2008 (online)

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Abstract

A facile route to naturally occurring (±)-norpandamarilactonines A and B, (±)-pandamarilactonines A-D, and pandanamine has been described from 3-methylfuran-2(5H)-one, with a reductive intramolecular aza-Michael-type addition as the key step.

Key words

3-methylfuran-2(5H)-one - condensation - intramolecular aza-Michael reaction - pandamarilactonines

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The stereochemical assignments of compounds 10, 14, 15, 17, and 18 are based on NMR parameters. [8]