DMW - Deutsche Medizinische Wochenschrift, Table of Contents Dtsch Med Wochenschr 2008; 133(14): 720DOI: 10.1055/s-2008-1067314 Pro & Contra | Commentary Pneumologie © Georg Thieme Verlag KG Stuttgart · New York Die Therapie der pulmonal-arteriellen Hypertonie bei COPD ist sinnvoll - pro The treatment of pulmonary arterial hypertension associated with chronic obstructive pulmonary disease makes sense - proH.-A Ghofrani1 1Medizinische Klinik II/V, Universitätsklinikum Gießen und Marburg GmbH Recommend Article Abstract Buy Article Schlüsselwörter pulmonal-arterielle Hypertonie - COPD - Endothelin-Antagonisten - Prostacyclin-Analoga - Phosphodiesterase-Inhibitoren Key words pulmonary hypertension - COPD - endothelin antagonists - prostacyclin analogues - phosphodiesterase inhibitors Full Text References Literatur 1 Alp S, Skrygan M, Schmidt W E, Bastian A. Sildenafil improves hemodynamic parameters in COPD-an investigation of six patients. Pulm Pharmacol Ther. 2006; 19 386-390 2 Ghofrani H A, Voswinckel R, Reichenberger F. et al . Hypoxia- and non-hypoxia-related pulmonary hypertension - established and new therapies. Cardiovasc Res. 2006; 72 30-40 3 MacNee W. Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part two. Am J Respir Crit Care Med. 1994; 150 1158-1168 4 Santos S, Peinado V I, Ramirez J. et al . Characterization of pulmonary vascular remodelling in smokers and patients with mild COPD. Eur Respir J. 2002; 19 632-638 Prof. Dr. Hossein-Ardeschir Ghofrani Medizinische Klinik II/V, Universitätsklinikum Gießen und Marburg GmbH Klinikstraße 36 35392 Gießen Email: ardeschir.ghofrani@innere.med.uni-giessen.de