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Synthesis 2008(18): 2879-2882  
DOI: 10.1055/s-2008-1067240
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

A Convenient and Practical Approach to α-Diketones via Reactions of Internal Aryl Alkynes with N-Iodosuccinimide/Water

Mingyu Niua, Hua Fu*a, Yuyang Jianga,b, Yufen Zhaoa
a Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. of China
b Key Laboratory of Chemical Biology, Guangdong Province, College of Shenzhen, Tsinghua University, Shenzhen 518057, P. R. of China
Fax: +86(10)62781695; e-Mail: fuhua@mail.tsinghua.edu.cn ;
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Publication History

Received 17 April 2008
Publication Date:
22 August 2008 (online)

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Abstract

A convenient and practical approach to α-diketones via reactions of alkynes with N-iodosuccinimides/water at 70 ˚C has been developed.

Key words

α-diketones - alkynes - N-iodosuccinimide - convenient and practical - water

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