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Synthesis 2008(18): 2899-2904
DOI: 10.1055/s-2008-1067221
DOI: 10.1055/s-2008-1067221
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New YorkApplication of 1-(3-Bromo-3,3-difluoroprop-1-ynyl)benzenes in Diels-Alder Reactions: Synthesis of ortho-CF2Br-Substituted Biaryls
Weitere Informationen
Received
26 March 2008
Publikationsdatum:
06. August 2008 (online)
Publikationsverlauf
Publikationsdatum:
06. August 2008 (online)

Abstract
1-(3-Bromo-3,3-difluoroprop-1-ynyl)benzenes were found to be good dienophiles in Diels-Alder reactions. Based on this key reaction a new pathway towards biaryls with an ortho-CF2Br group was elaborated.
Key words
alkynes - biaryls - bicyclic compounds - Diels-Alder reaction - fluorine
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