Direct Synthesis of Iodoarenes from Aromatic Substrates Using Molecular ­Iodine

Abstract

Easy laboratory procedures for oxidative iodination of aromatic substrates are presented. One procedure includes the iodination using molecular iodine, concentrated sulfuric acid, and potassium peroxodisulfate, and another uses a reagent system containing molecular iodine, potassium peroxodisulfate, and tri­fluoroacetic acid. These procedures are especially effective for benzene and less deactivated aromatic substrates, such as halobenzenes, trifluoromethylbenzene, and benzoic acid.

Key words

arenes - molecular iodine - iodoarenes - iodination - potassium peroxodisulfate

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