One-Pot Synthesis of Carbazoles via Subse-quent N-Arylation and Oxidative Coupling

Significance

This one-pot synthesis of functionalized carbazoles proceeds via N-arylation and subsequent oxidative C-H activation. Both reactions are promoted by a common palladium catalyst. Sensitive functionalities, such as ester groups, are tolerated. The corresponding carbazoles are received in good to excellent yields. It is noteworthy that the N-arylation step in many cases proceeded almost quantitatively, showing that the final yield mainly depends on the subsequent C-H activation.