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Synthesis 2007(24): 3776-3778  
DOI: 10.1055/s-2007-990908
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

Simple and Efficient Synthesis of N-Quaternary Salts of Quinuclidinium Derivatives

Jean-Yves Kazock*a, Mohamed Taggouguia, Bernard Carréa, Patrick Willmannb, Daniel Lemordanta
a Laboratoire Chimie Physique des Interfaces et des Milieux Electrolytiques, Faculté des Sciences, Université de Tours, Parc de Grandmont, Bat. J, 37200 Tours, France
Fax: +33(2)47367073; e-Mail: jykazock@yahoo.fr;
b CNES, 18 Avenue E. Belin, 31055 Toulouse cedex, France
Further Information

Publication History

Received 28 June 2007
Publication Date:
15 November 2007 (online)

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Abstract

The rapid and efficient synthesis of 1-alkylquinuclidinium (1-alkyl-1-azabicyclo[2.2.2]octane) and 1-alkyl-4-aza-1-azo­nia­bicyclo[2.2.2]octane iodides are described. The products were characterized by 1H NMR spectra and elemental analysis.

Key words

amines - alkyl halides - alkylation - ammonium - ionic liquids

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