Abstract
A simple and effective methodology for Claisen-Schmidt condensation of (-)-menthone
and other hindered cyclic ketones with aromatic aldehydes under highly basic conditions
using a polar aprotic solvent and a strong base (alkali metal hydroxide or an alkoxide)
is described and discussed.
Key words
aldehydes - α,β-unsaturated ketones - condensation - diastereoselectivity - super
basic conditions
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