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Semin Respir Crit Care Med 2006; 27(5): 492-500
DOI: 10.1055/s-2006-954607
Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Cadaveric Donor Selection and Management

Sean M. Studer1 , Jonathan B. Orens2
  • 1Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
  • 2Division of Pulmonary and Critical Care Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland
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Publication History

Publication Date:
26 October 2006 (online)

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ABSTRACT

While there is little doubt that proper donor selection is extremely important to achieve good outcomes from transplantation, there are only limited data regarding the current criteria utilized to select the “ideal donor”. Importantly, there are not enough donor lungs available for all of those in need. Until an adequate supply of donor organs exists, lives will be lost on the transplant waiting list. While efforts have been made to increase donor awareness, additional transplants can be realized by improving donor utilization. This can be achieved by active participation of transplant teams in donor management and by utilizing “extended criteria” organs. Further studies are needed to assess the impact of using “extended criteria” donors, as this practice could result in increased posttransplant morbidity and mortality. This article summarizes the approach to identification of potential lung donors, optimal donor management, and the clinical importance of various donor factors upon recipient outcomes.

KEYWORDS

Lung transplant - extended criteria - organ donation - organ procurement

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Jonathan B OrensM.D. 

Johns Hopkins Medical Institutions, Division of Pulmonary and Critical Care Medicine

1830 E. Monument St., 5th Fl., Baltimore, MD 21205

Email: jorens@jhmi.edu

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