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Synthesis 2006(8): 1246-1248  
DOI: 10.1055/s-2006-926409
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

A Convenient Synthesis of N-Substituted 2-Thioxo-1,3-thiazolidin-4-ones

Vladimir N. Yarovenko*a, Aleksandra S. Nikitinab, Igor V. Zavarzina, Mikhail M. Krayushkina, Leonid V. Kovalenkob
a N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991 Moscow, Russian Federation
Fax: +7(095)1355328; e-Mail: yarov@mail.ioc.ac.ru;
b D. I. Mendeleev Russian University of Chemical Technology, 9 pl. Miusskaya, Moscow 125047, Russian Federation
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Publikationsverlauf

Received 18 October 2005
Publikationsdatum:
27. März 2006 (online)

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Abstract

A convenient method was developed for the synthesis of N-substituted rhodanines based on the reaction of amines, hydrazides, or acid thiohydrazides with trithiocarbonyl diglycolic acid in the presence of dicyclohexylcarbodiimide or 1,1′-carbonyldiimidazole.

Key words

oxamic acid thiohydrazides - amines - hydrazides - rhodanines - carbodiimide - 1,1′-carbonyldiimidazole