Zwitterionic Compounds in the Synthesis of Water-Soluble 1,3-Oxathiolane Derivatives

Abstract

Perhydropyrimidin-2-ylium and perhydro-1,3-diazepin-2-ylium iodides with linked 1,3-oxathiolane ring were obtained. These new, water-soluble derivatives of 1,3-oxathiolane were prepared by cyclocondensation of diiodomethane with appropriate zwitterionic derivatives of 2-hydroxypropionic acid. The iodides were exploited in metathesis process with various anions.

Key words

zwitterionic compounds - saturated heterocycles - 1,3-oxathiolane - antimicrobial activity

References

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