Bronchioloalveolar carcinoma: A Review of the Epidemiology, Pathology, and Treatment

ABSTRACT

Bronchioloalveolar carcinoma (BAC) is an important subtype of pulmonary adenocarcinoma. It has received increasing attention in recent years, due to its increasing incidence and its rate of sensitivity to epidermal growth factor-tyrosine kinase inhibitors (EGFR-TKIs). This article reviews the epidemiology, risk factors, pathology, clinical presentation, and treatment of this disease. Special focus is paid to the emerging role of oral EGFR-TKIs in Bronchioloalveolar cell carcinoma.

KEYWORDS

Adenocarcinoma - Bronchioloalveolar - carcinoma - non-small cell lung - receptor - epidermal growth factor - smoking

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