Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000084.xml
Synthesis 2005(11): 1797-1800
DOI: 10.1055/s-2005-869905
DOI: 10.1055/s-2005-869905
PAPER
© Georg Thieme Verlag Stuttgart · New York
A New Synthetic Approach for the Synthesis of N2-Modified Guanosines
Further Information
Received
24 November 2005
Publication Date:
19 May 2005 (online)
Publication History
Publication Date:
19 May 2005 (online)

Abstract
A new universal route for generating N2-modified guanosines is developed and the synthesis of two examples is shown.
Key words
alkylations - alkyl halides - DNA - nucleosides - synthesis
- 1
Khan SI.Grinstaff MW. J. Am. Chem. Soc. 1999, 121: 4704 - 2
Wojczewski C.Stolze K.Engels JW. Synlett 1999, 1667 - 3
Schiemann O.Piton N.Mu Y.Stock G.Engels JW.Prisner TF. J. Am. Chem. Soc. 2004, 126: 5722 - 4
Uhlmann E.Peyman A. Chem. Rev. 1990, 90: 543 - 5
Schwarzer K. Dissertation Universität Frankfurt; Germany: 2002. -
6a
Lawley PD.Warren W. In DNA Repair: A Laboratory Manual of Research Procedures 1:Friedberg EC.Hanawalt P. Dekker; New York: 1981. p.129 -
6b
Osborne MR.Crosby NT. Benzopyrenes Cambridge University Press; Cambridge UK: 1987. p.147 - 7
Broom AD.Townsend LB.Jones JW.Robins RK. Biochemistry 1964, 3: 494 - 8
Harris CM.Zhou L.Strand EA.Harris TA. J. Am. Chem. Soc. 1991, 113: 4328 - 9
Gerster JF.Robins RK. J. Am. Chem. Soc. 1965, 87: 3752 - 10
Gerster JF.Robins RK. J. Org. Chem. 1966, 31: 3258 - 11
Schering AG,Vorbrüggen H,Krolikiewicz K,Baumann JD, andWirsching RC. inventors; German Patent DE 4141454A1. - 12
Adib A.Potier PF.Doronina S.Huc I.Behr J.-P. Tedrahedron Lett. 1997, 38: 2989 - 13
Potier P.Abdennaji A.Behr J.-P. Chem.-Eur. J. 2000, 6: 4188 - 14
Kasai H.Goto M.Ikeda K.Zama M.Mizuno Y.Takemura S.Matsuura S.Sugimoto T.Goto T. Biochemistry 1976, 15: 898 - 15
Glemarec C.Wu J.-C.Remaud G.Bazin H.Oivanen M.Lönnenberg H.Chattopadhyaya J. Tetrahedron 1988, 44: 1273 - 16
Ostrowski T.Zeidler J.Goslinski T.Golankiewicz B. Nucleosides, Nucleotides Nucleic Acids 2000, 19: 1911 - 17
Levene PA. Org. Synth. 1930, 10: 12