Abstract
A convenient method leading to fused pyrido[1,2-a ] [1,3,5]triazine-2-ones is described. It consists in a one-pot, two-step reaction
of N -(2′-pyridinyl)benzoylacetamide with nitrosobenzenes. On the other hand, N -(2′-pyridinyl)acetoacetamide provides a C-2 condensation/addition product with nitrosobenzene.
N -(2′-Pyridinyl)benzoylthioacetamide and N -(2′-pyridinyl)acetothioacetamide with nitrosobenzene undergo oxidative heterocyclisation
leading to [1,2,4]thiadiazolo[2,3-a ]pyridine derivatives.
Key words
amides - heterocycles - pyridotriazines - thiadiazolopyridines - cycloadditions
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