A New and Facile Iodine(III)-Mediated Approach for the Regioselective Alkoxylation of 2,5-Dihydroxyacetophenone

Om Prakash; Rashmi Pundeer; Harpreet Kaur

doi:10.1055/s-2003-42461

SHORTPAPER

A New and Facile Iodine(III)-Mediated Approach for the Regioselective Alkoxylation of 2,5-Dihydroxyacetophenone

Om Prakash*, Rashmi Pundeer, Harpreet Kaur
Chemistry Department, Kurukshetra University, Kurukshetra, Haryana 136119, India
Fax: +91(1744)238277; e-Mail: oprakash50@sify.com;

Abstract

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Abstract

Oxidation of 2,5-dihydroxyacetophenone with iodobenzene diacetate (IBD) in different alcohols leads to regioselective alkoxylation, thereby providing a new and convenient route for the synthesis of 6-alkoxy-2,5-dihydroxyacetophenones.

Key words

hypervalent iodine - regioselective alkoxylation - 2,5-dihydroxyacetophenone - iodobenzene diacetate - oxidations

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References

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