Clay Catalysed Synthesis of Dihydropyrimidinones under Solvent-free Conditions

Alok Kumar Mitra; Krishna Banerjee

doi:10.1055/s-2003-40828

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Synlett 2003(10): 1509-1511
DOI: 10.1055/s-2003-40828

LETTER

Clay Catalysed Synthesis of Dihydropyrimidinones under Solvent-free Conditions

Alok Kumar Mitra*, Krishna Banerjee
Department of Chemistry, University of Calcutta, 92 Acharya P.C. Road, Calcutta - 700 009, India
Fax: +91(33)3519755; e-Mail: akmitra@cucc.ernet.in;

Further Information

Publication History

Received 4 November 2002
Publication Date:
24 July 2003 (online)

Abstract
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Abstract

A fast and high yielding one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones from β-keto esters, urea and various aliphatic and aromatic aldehydes using montmorillonite KSF clay as a catalyst in solvent-free condition under microwave irradiation is described. The catalyst can also be recycled in these syntheses.

Key words

dihydropyrimidinones - montmorillonite KSF - microwave activation - solvent-free condition

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