Rhodium-Catalyzed [5+2] Cycloaddition Reactions in Water

Abstract

A new water-soluble rhodium catalyst is reported along with its ability to effect [5+2] cycloaddition reactions in water. This water-soluble catalyst is recyclable, is readily separated from the organic product, and allows one to avoid or minimize the use of organic solvents, the major waste stream of most organic reactions.

Key words

water-soluble catalyst - biphasic reactions - cycloaddition - medium-sized rings - rhodium

References

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Commercially available from Strem Chemicals: $121.00 for 1 g, catalog # 15-0155.