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Am J Perinatol 2001; 18(5): 237-240
DOI: 10.1055/s-2001-16988
ORIGINAL ARTICLES

Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Human Parvovirus B19 in Cord Blood of Premature Infants

Mayumi Koga1 3 , Takashi Matsuoka1 , Kumiko Katayama1 , Kanae Takeda1 3 , Masahiko Nakata2 3 , Masakatsu Sase2 3 , Hiroshi Kato2 3 , Susumu Furukawa1 3
  • 1Department of Pediatrics, Yamaguchi University School of Medicine, Yamaguchi, Japan
  • 2Department of Gynecology, Yamaguchi University School of Medicine, Yamaguchi, Japan
  • 3Department of Perinatal Care Center for Mother and Child, Yamaguchi University School of Medicine, Yamaguchi, Japan
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Publication Date:
10 September 2001 (online)

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ABSTRACT

We investigated whether intrauterine parvovirus B19 infection is associated with premature birth by evaluating parvovirus B19 antibodies and DNA in umbilical cord blood from 76 premature infants. We performed enzyme-linked immunoadsorbent (ELISA) and polymerase chain reaction (PCR) assays to detect B19-specific IgM antibodies and parvovirus DNA. No parvovirus DNA was detected in cord blood sera, and no sample was positive for anti-parvovirus B19 IgM antibodies. Parvovirus appears unlikely to lead to premature birth.

KEYWORD

Parvovirus - cord blood - premature infant - polymerase chain reaction

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