Aneurysm of the Ductus Arteriosus in a Neonate with 13q-Deletion

ABSTRACT

Aneurysm of the ductus arteriosus is a rare abnormality for which different ways of pathogenesis are described. We report the case of a fatal thrombosis of an aneurysm of the ductus arteriosus in an infant presenting feeding difficulties and a mild dysmorphic facies. Karyotype analysis revealed a de novo chromosomal deletion 46,XY, del (13)(q12.3,q22.3). To the best of our knowledge, this is the first case of an aneurysm of the ductus arteriosus associated with a chromosomal aberration.

KEYWORD

Chromosome 13 - deletion - aneurysm - ductus arteriosus - congenital heart disease

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