Aneurysm of the Ductus Arteriosus in a Neonate with 13q-Deletion

G. Naulaers; K. Devriendt; Ph. Moerman; P. Gillis; C. Vanhole; H. Devlieger

doi:10.1055/s-2001-12936

American Journal of Perinatology, Table of Contents

Am J Perinatol 2001; 18(1): 011-014
DOI: 10.1055/s-2001-12936

Original Articles
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Aneurysm of the Ductus Arteriosus in a Neonate with 13q-Deletion

G. Naulaers¹ , K. Devriendt² , Ph. Moerman³ , P. Gillis⁴ , C. Vanhole¹ , H. Devlieger¹

¹Neonatal Intensive Care Unit, Department of Paediatrics, UZ Gasthuisberg, Leuven, Belgium
²Centre for Human Genetics, UZ Gasthuisberg, Leuven, Belgium
³Department of Pathology, UZ Gasthuisberg, Leuven, Belgium
⁴Department of Paediatrics, Virga Jesse Ziekenhuis, Hasselt, Belgium

Abstract

ABSTRACT

Aneurysm of the ductus arteriosus is a rare abnormality for which different ways of pathogenesis are described. We report the case of a fatal thrombosis of an aneurysm of the ductus arteriosus in an infant presenting feeding difficulties and a mild dysmorphic facies. Karyotype analysis revealed a de novo chromosomal deletion 46,XY, del (13)(q12.3,q22.3). To the best of our knowledge, this is the first case of an aneurysm of the ductus arteriosus associated with a chromosomal aberration.

KEYWORD

Chromosome 13 - deletion - aneurysm - ductus arteriosus - congenital heart disease

Full Text

References

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