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Thorac Cardiovasc Surg 2024; 72(08): 614-623
DOI: 10.1055/s-0043-1769099
Original Cardiovascular

Transapical Transcatheter Mitral Valve Implantation with the Tendyne Valve: The Swiss Experience

Maria Nucera    *
1   Department of Cardiac Surgery, Cardiovascular Center, Inselspital University Hospital Bern, Bern, Switzerland
,
Jules Miazza   *
2   Department of Cardiac Surgery, Universitätsspital Basel, Basel, BS, Switzerland
,
Fabien Praz
3   Department of Cardiology, Inselspital University Hospital Bern, Bern, Switzerland
,
Christoph Kaiser
4   Department of Cardiology, Universitätsspital Basel, Basel, BS, Switzerland
,
Matthias Siepe
1   Department of Cardiac Surgery, Cardiovascular Center, Inselspital University Hospital Bern, Bern, Switzerland
,
David Reineke   **
1   Department of Cardiac Surgery, Cardiovascular Center, Inselspital University Hospital Bern, Bern, Switzerland
,
Oliver Reuthebuch    **
2   Department of Cardiac Surgery, Universitätsspital Basel, Basel, BS, Switzerland
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Abstract

Background The aim of this study was to report outcomes of all patients undergoing transcatheter mitral valve implantation with the Tendyne Mitral Valve System (Tendyne) in Switzerland.

Methods We retrospectively analyzed preoperative echocardiographic and computed tomography (CT) data, procedural findings, and 30-day and 1-year follow-up echocardiographic and clinical data of patients who underwent transcatheter mitral valve implantation with Tendyne in Switzerland.

Results A total of 24 patients (age, 74.8 ± 7.8 years; 67% male) underwent transapical transcatheter mitral valve implantation with Tendyne between June 2020 and October 2022. Technical success rate was 96%. In five patients, concomitant interventions in the form of transcatheter aortic valve implantation (one patient), minimally invasive direct coronary artery bypass (one patient), and transcatheter edge-to-edge repair (three patients) were performed prior to or after the index procedure. There was one device embolization, and two patients required valve retrieval. In-hospital outcomes included one stroke and three major bleeding events. None of the patients died within 30 days. Two patients were rehospitalized for decompensated heart failure. At 1-year follow-up, there were three noncardiovascular-related deaths.

Conclusion Transcatheter mitral valve implantation with Tendyne is feasible to treat polymorbid patients suffering from complex mitral valve disease as well as patients with previous mitral interventions. Perioperative risk was acceptable and procedural success high.

Keywords

mitral valve - mitral valve disease - transcatheter mitral valve replacement

Data Availability Statement

Raw data were generated at University Hospital Bern and at University Hospital Basel. All relevant data are within the manuscript.


Authors' Contribution

The study was undertaken in equal parts in Bern and Basel. D.R. and O.R. have selected the patients, done the procedures, and are therefore in equal parts at the origin of this work. They have initiated the publication of the data and designed its outlines. They have treated the patients, collected their consent and done the in-house follow-up, designed the paper, and edited the article with focus on the patients at their centers. The same applies for the first authors, who had corresponding roles at their centers, doing follow-up for their patients, getting the ethic committees approval for their respective patients, and writing the document. The same applied for the review. The only thing that was done exclusively in one center is the filming of the procedure.


* These authors contributed equally to this manuscript and are joint first authors.


** These authors contributed equally to this manuscript and are joint last authors.




Publikationsverlauf

Eingereicht: 17. November 2022

Angenommen: 13. April 2023

Artikel online veröffentlicht:
16. Juni 2023

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