Thorac Cardiovasc Surg 2024; 72(08): 607-613
DOI: 10.1055/s-0043-1762940
Original Cardiovascular

Minimally Invasive Mitral Valve Surgery in the Elderly

Maximilian Franz
1   Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
,
Nunzio Davide De Manna
2   Division of Cardiac Surgery, Cardiothoracic Department, University Hospital, Udine, Italy
,
Saskia Schulz
1   Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
,
Fabio Ius
1   Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
,
Axel Haverich
1   Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
,
Serghei Cebotari
1   Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
,
Igor Tudorache
3   Department of Cardiac Surgery, University Hospital Düsseldorf, Düsseldorf, Germany
,
Jawad Salman
1   Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
› Author Affiliations

Abstract

Background The minimally invasive mitral valve procedure warrants minimal surgical trauma and might influence the postoperative course positively, especially in old patients. In this retrospective study, we reviewed our experience in minimally invasive mitral valve surgery (miMVS) in patients aged ≥ 75 years.

Methods In this retrospective cohort study, based on propensity score matching, we compared patients aged ≥75 years with patients aged <75 years who underwent miMVS. The primary endpoint was 30-day mortality. Secondary endpoints were myocardial infarction, stroke, and renal failure.

Results Between January 2011 and February 2021, 761 patients underwent miMVS at our institution. After propensity score matching, a study group (≥75 years, n = 189) and a control group (<75 years, n = 189) were formed. Preoperatively patients ≥75 years more often suffered from NYHA III heart failure (60 vs. 46%; p = 0.013). Their valves were more often frequently replaced (48 vs. 32%; p < 0.001), and their postoperative ventilation time was longer (13 hours vs. 11 hours; p < 0.001). There were no statistically significant differences regarding postoperative stroke (3 vs. 0.6%; p = 0.16), myocardial infarction (0 vs. 1%; p = 0.32), renal insufficiency with new dialysis (5 vs. 4%; p = 0.62), and 30-day mortality (4 vs. 2%; p = 0.56).

Conclusion miMVS results in satisfactory early postoperative outcomes in elderly patients.



Publication History

Received: 03 July 2022

Accepted: 10 January 2023

Article published online:
01 March 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Volk L, Chao J, Dombrovskiy V. et al. Impact of risk factors on in-hospital mortality for octogenarians undergoing cardiac surgery. J Card Surg 2021; 36 (07) 2400-2406
  • 2 Feldman T, Foster E, Glower DD. et al; EVEREST II Investigators. Percutaneous repair or surgery for mitral regurgitation. N Engl J Med 2011; 364 (15) 1395-1406
  • 3 Mack MJ. Percutaneous mitral valve repair: a fertile field of innovative treatment strategies. Circulation 2006; 113 (19) 2269-2271
  • 4 Sondergaard L, Brooks M, Ihlemann N. et al. Transcatheter mitral valve implantation via transapical approach: an early experience. Eur J Cardiothorac Surg 2015; 48 (06) 873-877 , discussion 877–878
  • 5 Andalib A, Mamane S, Schiller I. et al. A systematic review and meta-analysis of surgical outcomes following mitral valve surgery in octogenarians: implications for transcatheter mitral valve interventions. EuroIntervention 2014; 9 (10) 1225-1234
  • 6 Seeburger J, Raschpichler M, Garbade J. et al. Minimally invasive mitral valve surgery in octogenarians---a brief report. Ann Cardiothorac Surg 2013; 2 (06) 765-767
  • 7 Minol JP, Akhyari P, Boeken U. et al. Single-centre experience of mitral valve surgery via right lateral mini-thoracotomy in octogenarians. Interact Cardiovasc Thorac Surg 2016; 22 (03) 287-290
  • 8 Chikwe J, Goldstone AB, Passage J. et al. A propensity score-adjusted retrospective comparison of early and mid-term results of mitral valve repair versus replacement in octogenarians. Eur Heart J 2011; 32 (05) 618-626
  • 9 Badhwar V, Peterson ED, Jacobs JP. et al. Longitudinal outcome of isolated mitral repair in older patients: results from 14,604 procedures performed from 1991 to 2007. Ann Thorac Surg 2012; 94 (06) 1870-1877 , discussion 1877–1879
  • 10 Schmidtler FW, Tischler I, Lieber M. et al. Cardiac surgery for octogenarians---a suitable procedure? Twelve-year operative and post-hospital mortality in 641 patients over 80 years of age. Thorac Cardiovasc Surg 2008; 56 (01) 14-19
  • 11 Carpentier A. Cardiac valve surgery---the “French correction”. J Thorac Cardiovasc Surg 1983; 86 (03) 323-337
  • 12 Thygesen K, Alpert JS, Jaffe AS. et al; Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction. Fourth Universal Definition of Myocardial Infarction (2018). J Am Coll Cardiol 2018; 72 (18) 2231-2264
  • 13 Shapira U, Krubiner M, Ehrenwald M. et al. Eosinophil levels predict lung function deterioration in apparently healthy individuals. Int J Chron Obstruct Pulmon Dis 2019; 14: 597-603
  • 14 Salman J, Fleißner F, Naqizadah J. et al. Minimally invasive mitral valve surgery in re-do cases---the new standard procedure?. Thorac Cardiovasc Surg 2018; 66 (07) 545-551
  • 15 Omran AS, Arifi AA, Mohamed AA. Echocardiography in mitral stenosis. J Saudi Heart Assoc 2011; 23 (01) 51-58
  • 16 Chew PG, Bounford K, Plein S, Schlosshan D, Greenwood JP. Multimodality imaging for the quantitative assessment of mitral regurgitation. Quant Imaging Med Surg 2018; 8 (03) 342-359
  • 17 Chivasso P, Bruno VD, Farid S. et al. Predictors of survival in octogenarians after mitral valve surgery for degenerative disease: the mitral surgery in octogenarians study. J Thorac Cardiovasc Surg 2018; 155 (04) 1474-1482.e2
  • 18 Fleißner F, Salman J, Naqizadah J. et al. Minimally invasive surgery in mitral valve endocarditis. Thorac Cardiovasc Surg 2019; 67 (08) 637-643
  • 19 Wang W, Bagshaw SM, Norris CM, Zibdawi R, Zibdawi M, MacArthur R. APPROACH Investigators. Association between older age and outcome after cardiac surgery: a population-based cohort study. J Cardiothorac Surg 2014; 9: 177
  • 20 Moskowitz G, Hong KN, Giustino G. et al. Incidence and risk factors for permanent pacemaker implantation following mitral or aortic valve surgery. J Am Coll Cardiol 2019; 74 (21) 2607-2620
  • 21 Feldman T, Kar S, Elmariah S. et al; EVEREST II Investigators. Randomized comparison of percutaneous repair and surgery for mitral regurgitation: 5-year results of EVEREST II. J Am Coll Cardiol 2015; 66 (25) 2844-2854
  • 22 Buzzatti N, Van Hemelrijck M, Denti P. et al. Transcatheter or surgical repair for degenerative mitral regurgitation in elderly patients: A propensity-weighted analysis. J Thorac Cardiovasc Surg 2019; 158 (01) 86-94 . e81.
  • 23 Bonaros N, Hoefer D, Oezpeker C. et al. Predictors of safety and success in minimally invasive surgery for degenerative mitral disease. Eur J Cardiothorac Surg 2022; 61 (03) 637-644