Rescue antegrade diathermic dilation of hyperplastic tissue at partially covered metallic stent after EUS-guided hepaticogastrostomy

Endoscopic ultrasonography-guided antegrade stenting (EUS-AGS) and EUS-guided hepaticogastrostomy (EUS-HGS) are suitable for obstructive jaundice associated with gastric outlet obstruction or surgically altered anatomy [1]. Recently, a long partially covered self-expandable metallic stent (LPC-SEMS) has been developed to prevent stent migration and bile leakage and allow safe and effective EUS-HGS. However, one disadvantage of the LPC-SEMS is tissue hyperplasia at the uncovered portion of the stent [2]. Here, we present the case of a patient who underwent a rescue procedure using antegrade diathermic dilation for hyperplastic tissue occlusion of an LPC-SEMS and for tumor ingrowth into an uncovered SEMS placed for EUS-AGS.

A 60-year-old man with unresectable gastric cancer was admitted with gastric outlet obstruction and obstructive jaundice. He had undergone EUS-AGS using an uncovered metallic stent and EUS-HGS using a LPC-SEMS (diameter 6 mm, length 120 mm, uncovered proximal portion 10 mm; Taewoong Medical, Seoul, Korea). He again developed obstructive jaundice 7 months later. Antegrade cholangiography via the LPC-SEMS revealed perihilar bile duct stricture due to hyperplasia at the LPC-SEMS ([Fig. 1]). It was not possible to pass a tapered endoscopic retrograde cholangiopancreatography (ERCP) catheter through the stricture ([Video 1]). We successfully dilated the stricture using 6-Fr wire-guided diathermic dilation (Cysto-Gastro-Set; Endo-Flex, Voerde, Germany) ([Fig. 2, ] [Video 1]). Antegrade cholangiography showed free drainage through the previously hyperplastic area at the uncovered portion of the stent. No stent was placed as the previously occluded LPC-SEMS was now patent ([Fig. 3]). Subsequent antegrade cholangiography revealed occlusion of the uncovered metallic stent due to tumor ingrowth ([Fig. 4 a]). Passage was successfully obtained with antegrade diathermic dilation ([Fig. 4 b]). Finally, an ultraslim uncovered SEMS (BileRush Selective, 5.7-Fr, diameter 10 mm; Piolax Medical Devices, Kanagawa, Japan) was placed using a stent-in-stent method, without complications ([Fig. 5], [Video 1]).

Fig. 1 Radiographic image from a 60-year-old man, showing perihilar bile duct stricture due to hyperplasia (arrows) at the long partially covered self-expandable metallic stent (LPC-SEMS), after endoscopic ultrasonography-guided hepaticogastrostomy 7 months earlier (inset: endoscopic image).

Video 1 Antegrade diathermic dilation and stenting technique to treat: (i) hyperplastic tissue occlusion of a long partially covered self-expanding metal stent (LPC-SEMS); and (ii) recurrent distal biliary obstruction by tumor ingrowth into an uncovered SEMS, following endoscopic ultrasonography-guided hepaticogastrostomy and antegrade stenting 7 months previously in a 60-year-old man.

Fig. 2 Radiographic image showing wire-guided antegrade diathermic dilation for hyperplastic tissue at the LPC-SEMS. a Before diathermic dilation; inset: endoscopic image. b After diathermic dilation.

Fig. 3 Radiographic image showing free drainage through the previously hyperplastic area (arrows) at the uncovered portion of the LPC-SEMS after wire-guided antegrade diathermic dilation.

Fig. 4 Radiographic images: a Tumor ingrowth in the uncovered self-expandable metallic stent in the distal bile duct, placed at endoscopic ultrasonography-guided antegrade procedure 7 months earlier. b Wire-guided antegrade diathermic dilation for the tumor ingrowth.

Fig. 5 Radiographic image showing antegrade placement of ultraslim uncovered self-expandable metallic stent using the stent-in-stent method (inset: endoscopic image).

Recurrent biliary obstruction caused by tissue hyperplasia is an unresolved major problem of the LPC-SEMS, and the optimal rescue technique has not been established. EUS-guided antegrade diathermic dilation has been recently reported [3] [4] [5]. To our knowledge, this is the first report of rescue for hyperplastic tissue occlusion of an LPC-SEMS that used wire-guided antegrade diathermic dilation with no need for secondary stenting. This rescue technique is a useful method of recanalization of an LPC-SEMS occluded by hyperplastic tissue.

Endoscopy_UCTN_Code_CPL_1AK_2AC

 

MissingLinkText

Competing interests

Dr. Kawakami is a consultant to and gives lectures for Piolax Medical Devices, Kanagawa, Japan. The other authors declare no conflict of interests for this article.

• References

• 1 Kawakami H, Kubota Y. Endoscopic ultrasonography-guided antegrade stenting combined with hepaticogastrostomy/hepaticojejunostomy using ultraslim instruments. Endoscopy 2017; 49: E88-E89
• 2 Nakai Y, Isayama H, Yamamoto N. et al. Safety and effectiveness of a long, partially covered metal stent for endoscopic ultrasound-guided hepaticogastrostomy in patients with malignant biliary obstruction. Endoscopy 2016; 48: 1125-1128
• 3 Kawakami H, Kuwatani M, Sakamoto N. Endoscopic ultrasound-guided antegrade diathermic dilation followed by self-expandable metallic stent placement for anastomotic stricture after hepaticojejunostomy (with video). Dig Endosc 2014; 26: 121-122
• 4 Kawakami H, Kuwatani M, Kawakubo K. et al. Endoscopic ultrasound-guided antegrade diathermic dilation followed by self-expandable metal stent placement for malignant distal biliary stricture. Endoscopy 2014; UCTN: 46 (Suppl. 01) E328-E329
• 5 Kawakami H, Kuwatani M, Kawakubo K. et al. Endoscopic ultrasonography-guided antegrade diathermic dilation for the treatment of complete obstruction of a pancreaticogastrostomy. Endoscopy 2014; UCTN: 46 (Suppl. 01) E517-E518