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Klin Monbl Augenheilkd 2016; 233(07): 808-812
DOI: 10.1055/s-0042-105155
Übersicht
Georg Thieme Verlag KG Stuttgart · New York

Keratitis – infektiös oder autoimmun?

Keratitis – Infectious or Autoimmune?
E. M. Messmer
Augenklinik, Klinikum der Universität München
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Publication History

eingereicht 21 December 2015

akzeptiert 02 March 2016

Publication Date:
28 July 2016 (online)

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Zusammenfassung

Die Histopathologie ist ein wichtiger Baustein in der Differenzierung von Keratitiden in infektiöse und nicht infektiöse Entitäten. In beiden Keratitisformen treten Entzündungen, oft verbunden mit Nekrose und Keratolyse auf. Die histologische Untersuchung ist besonders bedeutsam in der Identifizierung von Erregern, der Diagnosestellung und/oder im Verlauf bei Herpes-simplex-Viruskeratitis, mykotischer Keratitis, Akanthamöbenkeratitis und Mikrosporienkeratokonjunktivitis. Wertvolle pathogenetische Hinweise mit therapeutischer Relevanz konnten histopathologische Studien liefern bei Nummuli nach Keratoconjunctivitis epidemica und atopischer Keratokonjunktivitis.

Abstract

Histopathological evaluation of ocular tissues is important in differentiating between infectious and autoimmune disease. Inflammation, necrosis and keratolysis are common to most forms of keratitis. Histopathology can be of great help in identifying the causative organism, establishing a final diagnosis and/or managing the patient with herpes simplex virus keratitis, mycotic keratitis, acanthamoeba keratitis or microsporidia keratoconjunctivitis. Important pathogenetic knowledge with therapeutic relevance has been gained from histopathological studies in nummular keratitis after epidemic keratoconjunctivitis and atopic keratoconjunctivitis.

Schlüsselwörter

Kornea - Mikrobiologie - Pathologie

Key words

cornea - microbiology - pathology
 

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