Abstract
The proximal tibia and distal femur are intimately linked with the biomechanics of
the knee and they are to be considered in total knee arthroplasty (TKA). The aim of
the present study was to evaluate the proximal tibial torsion (PTT) in relation to
surgical epicondylar axis (SEA) in a healthy cohort and a pathological cohort affected
by knee osteoarthritis (OA). We retrospectively analyzed computed tomography of OA
knee of 59 patients before they underwent TKA and nonarthritic knee of 39 patients
as control. Posterior condylar angle (PCAn), femoral tibial torsion (SEA-proximal
tibial condyle [PTC] and SEA-PTT), PTT (PTC-PTT and posterior condylar axes [PCAx]-PTC),
and distance between tibial tuberosity and the trochlear groove (TT-TG) were measured.
No differences were found for gender, age, TT-TG, and PCAn angles. Statistically significant
differences were found for all the other angles considered. Significant correlation
was found between tibial torsion and SEA-PTT angles, between PCAx-PTC and SEA-PTC,
between SEA-PTT and SEA-PTC, and between PCAx-PTC and SEA-PTT. All measures, except
TT-TG and PCAn angles, showed high validity (area under the curve [AUC] > 75%) in
associating with OA, with SEA-PTT displaying the highest validity with an AUC of 94.38%.
This is the first study to find significant differences in terms of proximal tibia
geometry and anatomy between nonarthritic and OA knees. From our results, we reported
that OA group was characterized by a greater internal rotation of tibia with respect
to SEAs compared with control group. Since the design of the study cannot evaluate
a cause–effect relationship, further studies need to be performed to assess the potential
implications of these anatomic differences for knee OA and arthroplasty surgeries.
Keywords
knee arthroplasty - osteoarthritis - tibia alignment - proximal tibial torsion - surgical
epicondylar axis
