Eur J Pediatr Surg 2020; 30(03): 251-260
DOI: 10.1055/s-0040-1713178
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Health-Related Quality of Life in Patients with the Bladder Exstrophy-Epispadias Complex and Relationship to Incontinence and Sexual Factors: A Review of the Recent Literature

Gundela Holmdahl
1   Department of Pediatric Surgery, Karolinska University Hospital, Astrid Lindgren Children’s Hospital, Stockholm, Sweden
2   Department of Pediatric Surgery, Pediatric Uronephrologic Center at the Queen Silvia Childrens Hospital, Institution of Clinical Sciences, Sahlgrenskas University Hospital, Gothenburg Sweden
,
Michaela Dellenmark-Blom
2   Department of Pediatric Surgery, Pediatric Uronephrologic Center at the Queen Silvia Childrens Hospital, Institution of Clinical Sciences, Sahlgrenskas University Hospital, Gothenburg Sweden
,
Agneta Nordenskjöld
1   Department of Pediatric Surgery, Karolinska University Hospital, Astrid Lindgren Children’s Hospital, Stockholm, Sweden
3   Department of Women’s and Children’s Health and Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden
,
Sofia Sjöström
2   Department of Pediatric Surgery, Pediatric Uronephrologic Center at the Queen Silvia Childrens Hospital, Institution of Clinical Sciences, Sahlgrenskas University Hospital, Gothenburg Sweden
› Author Affiliations
Further Information

Publication History

24 April 2020

08 May 2020

Publication Date:
21 June 2020 (online)

Abstract

The bladder exstrophy-epispadia complex (BEEC) includes malformations with midline closing defects of the lower abdomen and external genitalia. Long-term consequences with urinary incontinence and sexual dysfunction, in spite of multiple surgical interventions, are common and expected to affect the patient's health-related quality of life (HRQOL). The extent and the predictive factors are, however, not known. New patient-reported outcome research is emerging, but valid and reliable condition-specific HRQOL are still missing. The aim of this review is to summarize and discuss the latest published reports (2015–2019) on HRQOL in patients with the BEEC and its relationship to incontinence and sexual factors.

 
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