Synthesis 2020; 52(10): 1531-1540
DOI: 10.1055/s-0039-1691599
paper
© Georg Thieme Verlag Stuttgart · New York

Catalyst- and Solvent-Free Synthesis of α-Amino Polyfluoroalkylphosphonates from Bis(fluoroalkyl) Phosphonates and Aldimines

Authors

  • Svetlana N. Arbuzova

  • Nina K. Gusarova

  • Tatyana I. Kazantseva

  • Svetlana I. Verkhoturova

  • Sergey V. Zinchenko

  • Nikita A. Kolyvanov

  • Boris A. Trofimov

    A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, 1 Favorsky Str., 664033 Irkutsk, Russian Federation   Email: boris_trofimov@irioch.irk.ru

This work has been approved by plans for research projects at the IPC RAS State Registration No. AAAA-A16-116112510005-7.
Further Information

Publication History

Received: 12 December 2019

Accepted after revision: 19 January 2020

Publication Date:
13 February 2020 (online)


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Abstract

The catalyst- and solvent-free reaction between bis(fluoroalkyl) phosphonates and aldimines occurs under mild conditions (20–22 °C, 0.25–4 h) to afford a new family of α-amino polyfluoroalkylphosphonates in up to quantitative yields.

Supporting Information