Synlett 2020; 31(11): 1126-1128
DOI: 10.1055/s-0039-1690902
letter
© Georg Thieme Verlag Stuttgart · New York

Hantzsch-Like Three-Component Synthesis of 9,10-Dihydro-3H-10a-azaphenanthrene-2,4-dicarbonitriles

Fatma M. Saleh
,
Hamdi M. Hassaneen
,
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Publikationsverlauf

Received: 08. März 2020

Accepted after revision: 02. April 2020

Publikationsdatum:
22. April 2020 (online)


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Abstract

A novel series of 9,10-dihydro-3H-10a-azaphenanthrene-2,4-dicarbonitrile derivatives that contain a bridgehead nitrogen were prepared by a three-component reaction of aldehydes, 2-(6,7-dimethoxy-3,4-dihydroisoquinolin-1-yl)acetonitrile, and 3-aminocrotononitrile in acetic acid.

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