RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2019; 15(11): 1285
DOI: 10.1055/s-0039-1690327
DOI: 10.1055/s-0039-1690327
Metals in Synthesis
The Hiyama–Denmark Cross-Coupling
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
18. Oktober 2019 (online)

Significance
The authors reported a fluoride-free palladium-catalyzed cross-coupling of organosilanols with iodoarenes. Previous conditions for palladium-catalyzed cross-coupling of organosilanes required high temperatures and long reaction times.
MissingLinkText
Review
S. E. Denmark, R. F. Sweis Acc. Chem. Res. 2002, 35, 835–846.
MissingLinkText
Comment
Various iodoarenes reacted with an organosilanol to provide the cross-coupled products in high yields. The authors propose that a second molecule of silyloxide binds to the arylpalladium silyloxide to generate a pentacoordinate silicon intermediate, which can undergo a facile transmetalation.
MissingLinkText
MissingLinkText
