Abstract
Progress in neonatal care has decrease morbidity and mortality due to neonatal sepsis
(NS). Although diagnosis of sepsis continues to rely on blood culture, this method
is too slow and limited by false-negative results. There are numerous sepsis biomarkers
that have been evaluated for the early diagnosis of NS, but, to date, there is no
single ideal biomarker, though novel biomarkers are becoming more sophisticated and
specific in their clinical applications. This review provides an overview of the current
diagnostic approaches available or under development for diagnosing NS.
Keywords
neonate - sepsis - biomarkers - diagnosis